Acute beetroot juice reduces blood pressure in young Black and White males but not females.

Autor: Grosicki GJ; Biodynamics and Human Performance Center, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Flatt AA; Biodynamics and Human Performance Center, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Cross BL; Biodynamics and Human Performance Center, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Vondrasek JD; Biodynamics and Human Performance Center, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Blumenburg WT; Biodynamics and Human Performance Center, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Lincoln ZR; Biodynamics and Human Performance Center, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Chall A; Department of Diagnostic and Therapeutic Services, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Bryan A; Department of Diagnostic and Therapeutic Services, Georgia Southern University, Armstrong Campus, Savannah, GA, USA., Patel RP; Department for Pathology and Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Ricart K; Department for Pathology and Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Linder BA; Neurovascular Physiology Laboratory, Auburn University, Auburn, AL, USA., Sanchez SO; Neurovascular Physiology Laboratory, Auburn University, Auburn, AL, USA., Watso JC; Cardiovascular and Applied Physiology Laboratory, Florida State University, Tallahassee, FL, USA., Robinson AT; Neurovascular Physiology Laboratory, Auburn University, Auburn, AL, USA. Electronic address: https://twitter.com/AusRob_PhD.
Jazyk: angličtina
Zdroj: Redox biology [Redox Biol] 2023 Jul; Vol. 63, pp. 102718. Date of Electronic Publication: 2023 Apr 25.
DOI: 10.1016/j.redox.2023.102718
Abstrakt: A complex interplay of social, lifestyle, and physiological factors contribute to Black Americans having the highest blood pressure (BP) in America. One potential contributor to Black adult's higher BP may be reduced nitric oxide (NO) bioavailability. Therefore, we sought to determine whether augmenting NO bioavailability with acute beetroot juice (BRJ) supplementation would reduce resting BP and cardiovascular reactivity in Black and White adults, but to a greater extent in Black adults. A total of 18 Black and 20 White (∼equal split by biological sex) young adults completed this randomized, placebo-controlled (nitrate (NO 3 - )-depleted BRJ), crossover design study. We measured heart rate, brachial and central BP, and arterial stiffness (via pulse wave velocity) at rest, during handgrip exercise, and during post-exercise circulatory occlusion. Compared with White adults, Black adults exhibited higher pre-supplementation resting brachial and central BP (Ps ≤0.035; e.g., brachial systolic BP: 116(11) vs. 121(7) mmHg, P = 0.023). Compared with placebo, BRJ (∼12.8 mmol NO 3 - ) reduced resting brachial systolic BP similarly in Black (Δ-4±10 mmHg) and White (Δ-4±7 mmHg) adults (P = 0.029). However, BRJ supplementation reduced BP in males (Ps ≤ 0.020) but not females (Ps ≥ 0.299). Irrespective of race or sex, increases in plasma NO 3 - were associated with reduced brachial systolic BP (ρ = -0.237, P = 0.042). No other treatment effects were observed for BP or arterial stiffness at rest or during physical stress (i.e., reactivity); Ps ≥ 0.075. Despite young Black adults having higher resting BP, acute BRJ supplementation reduced systolic BP in young Black and White adults by a similar magnitude, an effect that was driven by males.
Competing Interests: Declaration of interest None.
(Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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