The Influence of Low-Level Laser Therapy on CBCT Radiographic and Biochemical Profiles of Type II Controlled Diabetic Patients After Dental Implant Insertion: A Randomized Case-Control Study.

Autor:	Attia MS; Department of Oral Medicine, Periodontology, Diagnosis, and Radiology, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, EGY.; Department of Periodontology, Oral Diagnosis, and Oral Radiology, Faculty of Oral and Dental Medicine, Misr International University, Cairo, EGY., Elewa GM; Department of Oral Medicine, Diagnosis, and Periodontology, Faculty of Oral and Dental Medicine, Delta University of Science and Technology, Gamasa, EGY., Abdelgawad N; Department of Oral Medicine, Periodontology, Diagnosis, and Radiology, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, EGY., Ismail RM; Department of Oral Medicine, Periodontology, and Oral Diagnosis, Faculty of Dentistry, Misr University for Science and Technology (MUST), Cairo, EGY., Hassan Eid M; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suez Canal University, Ismailia, EGY., Ghoneim MM; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Sinai University, El-Arish, EGY.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Mar 23; Vol. 15 (3), pp. e36559. Date of Electronic Publication: 2023 Mar 23 (Print Publication: 2023).
DOI:	10.7759/cureus.36559
Abstrakt:	Background Low-level laser treatment (LLLT) was thought to increase bone quality during osseointegration when combined with dental implants. However, there is no sufficient information on its impact on dental implants in diabetics. Osteoprotegerin (OPG) has been described as a marker for bone turnover to determine implant prognosis. The current research aims to evaluate the effect of low-level laser therapy (LLLT) on bone density (BD) and osteoprotegerin levels in peri-implant crevicular fluid (PICF) in type II diabetic patients. Methods This study comprised 40 individuals with type II diabetes mellitus (T2DM). Implants were randomly placed in 20 non-lasered T2DM patients (control) and 20 lasered T2DM patients (LLLT group). At the follow-up stages, BD and OPG levels in the PICF were evaluated in both groups. Results Significant variations were shown among control and LLLT groups concerning OPG level and BD (p≤0.001). OPG was significantly decreasing with follow-up points (p≤0.001). There was a significant decrease in OPG with time in both groups with a higher decrease in the control group. Conclusion LLLT is promising in controlled T2DM patients due to its outstanding influence on BD and estimated crevicular levels of OPG. Regarding its clinical significance, LLLT significantly improved bone quality during osseointegration on dental implants in T2DM. LLLT is considered potentially important for T2DM patients during implant placement. Trial registration The study was registered on ClinicalTrial.gov under registration number NCT05279911 (registration date: March 15, 2022) (https://clinicaltrials.gov/ct2/show/NCT05279911). Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Attia et al.)
Databáze:	MEDLINE
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