Myriad applications of bacteriophages beyond phage therapy.

Autor:	García-Cruz JC; Faculty of Medicine Department of Microbiology and Parasitology, Universidad Nacional de México, Mexico City, Mexico., Huelgas-Méndez D; Faculty of Medicine Department of Microbiology and Parasitology, Universidad Nacional de México, Mexico City, Mexico., Jiménez-Zúñiga JS; Faculty of Medicine Department of Microbiology and Parasitology, Universidad Nacional de México, Mexico City, Mexico., Rebollar-Juárez X; Faculty of Medicine Department of Microbiology and Parasitology, Universidad Nacional de México, Mexico City, Mexico., Hernández-Garnica M; Faculty of Medicine Department of Microbiology and Parasitology, Universidad Nacional de México, Mexico City, Mexico., Fernández-Presas AM; Faculty of Medicine Department of Microbiology and Parasitology, Universidad Nacional de México, Mexico City, Mexico., Husain FM; Department of Food Science and Nutrition, King Saud University, Riyadh, Saudi Arabia., Alenazy R; Department of Medical Laboratory, College of Applied Medical Sciences-Shaqra, Shaqra University, Shaqra, Saudi Arabia., Alqasmi M; Department of Medical Laboratory, College of Applied Medical Sciences-Shaqra, Shaqra University, Shaqra, Saudi Arabia., Albalawi T; Department of Biology, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia., Alam P; Department of Biology, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia., García-Contreras R; Faculty of Medicine Department of Microbiology and Parasitology, Universidad Nacional de México, Mexico City, Mexico.
Jazyk:	angličtina
Zdroj:	PeerJ [PeerJ] 2023 Apr 21; Vol. 11, pp. e15272. Date of Electronic Publication: 2023 Apr 21 (Print Publication: 2023).
DOI:	10.7717/peerj.15272
Abstrakt:	Bacteriophages are the most abundant biological entity on the planet, having pivotal roles in bacterial ecology, animal and plant health, and in the biogeochemical cycles. Although, in principle, phages are simple entities that replicate at the expense of their bacterial hosts, due the importance of bacteria in all aspects of nature, they have the potential to influence and modify diverse processes, either in subtle or profound ways. Traditionally, the main application of bacteriophages is phage therapy, which is their utilization to combat and help to clear bacterial infections, from enteric diseases, to skin infections, chronic infections, sepsis, etc . Nevertheless, phages can also be potentially used for several other tasks, including food preservation, disinfection of surfaces, treatment of several dysbioses, and modulation of microbiomes. Phages may also be used as tools for the treatment of non-bacterial infections and pest control in agriculture; moreover, they can be used to decrease bacterial virulence and antibiotic resistance and even to combat global warming. In this review manuscript we discuss these possible applications and promote their implementation. Competing Interests: Rodolfo García-Contreras is an Academic Editor for PeerJ. (© 2023 García-Cruz et al.)
Databáze:	MEDLINE
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