Technical note: Improved differentiation of calcification from hemosiderin using paramagnetic- and diamagnetic-specific magnetic resonance susceptibility weighted imaging (p-SWI, d-SWI).

Autor: Campeau NG; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address: campeau.norbert@mayo.edu., Trzasko JD; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA., Meyer NK; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA., Haider CR; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA., Huston J 3rd; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA., Bernstein MA; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Jazyk: angličtina
Zdroj: Clinical imaging [Clin Imaging] 2023 Jul; Vol. 99, pp. 47-52. Date of Electronic Publication: 2023 Apr 19.
DOI: 10.1016/j.clinimag.2023.04.009
Abstrakt: Introduction: Differentiation of calcification and calcium-containing tissue from blood products remains challenging using magnetic resonance imaging (MRI). We developed a novel post-processing algorithm which creates both paramagnetic- and diamagnetic-specific SWI images generated from T2* weighted images using distinct "positive" and "negative" phase masks.
Methods: 10 patients who had undergone clinical MRI scanning of the brain with a rapid echo planar based T2*-weighted EPI-GRE pulse sequence with evidence for either hemosiderin and/or calcifications were retrospectively identified. Complex raw k-space data from individual imaging coils were then extracted, reconstructed, and appropriately combined to produce magnitude and phase images using a phase preserving method. The final reconstructed images included the T2* EPI-GRE magnitude images, p-SWI and d-SWI images. Filtered phase images were also available for review. Correlation with CT scans and MR imaging appearance over time corroborated the composition of the voxels.
Results: Differential "blooming" of diamagnetic and paramagnetic foci was readily identified on the corresponding p-SWI and d-SWI images and provided fast and reliable visual differentiation of diamagnetic from paramagnetic susceptibility effects by ascertaining which of the two images depicted the greatest "blooming" effect. Correlation with the available filtered phase maps was not necessary for differentiation of paramagnetic from diamagnetic image components.
Conclusion: Clinical interpretation of SWI images can be further enhanced by creating specific p-SWI and d-SWI image pairs which contain greater visual information than the combination of standard p-SWI images and phase image.
Competing Interests: Declaration of competing interest None from all authors. Funded in part by NIH grant U01 EB02445.
(Published by Elsevier Inc.)
Databáze: MEDLINE
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