Oral hygiene and infective endocarditis: a case control study.

Autor: Lockhart PB; Department of Oral Medicine/Oral & Maxillofacial Surgery, Atrium Health's Carolinas Medical Center, Charlotte, NC, USA. Electronic address: peterLockhart@Atriumhealth.org., Chu V; Department of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, NC, USA., Zhao J; Atrium Health Center for Outcomes Research and Evaluation, Charlotte, NC, USA., Gohs F; Atrium Health Center for Outcomes Research and Evaluation, Charlotte, NC, USA., Thornhill MH; Department of Oral Medicine/Oral & Maxillofacial Surgery, Atrium Health's Carolinas Medical Center, Charlotte, NC, USA; Department of Oral and Maxillofacial Medicine, Oral Surgery and Oral Pathology, University of Sheffield, School of Clinical Dentistry, Sheffield, UK., Pihlstrom B; Department of Developmental and Surgical Sciences, University of Minnesota, School of Dentistry, Minneapolis, MN, USA., Mougeot FB; Department of Oral Medicine, Atrium Health's Carolinas Medical Center, Microbiome Research Laboratory, Charlotte, NC, USA., Rose GA; Sanger Heart & Vascular Institute, Charlotte, NC, USA., Sun YP; Cardiovascular Medicine Division, Brigham and Women's Hospital, Boston, MA, USA., Napenas J; Department of Oral Medicine/Oral & Maxillofacial Surgery, Atrium Health's Carolinas Medical Center, Charlotte, NC, USA., Munz S; Department of Oral & Maxillofacial Surgery/Hospital Dentistry, University of Michigan, Ann Arbor, MI, USA., Farrehi PM; Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Sollecito T; Department of Oral Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sankar V; Division of Oral Medicine, Brigham and Women's Hospital, Boston, MA, USA; Department of Diagnostic Sciences, Tufts University School of Dentistry, Boston, MA, USA., O'Gara PT; Cardiovascular Medicine Division, Brigham and Women's Hospital, Boston, MA, USA.
Jazyk: angličtina
Zdroj: Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2023 Sep; Vol. 136 (3), pp. 333-342. Date of Electronic Publication: 2023 Mar 11.
DOI: 10.1016/j.oooo.2023.02.020
Abstrakt: Objective: To determine if oral hygiene is associated with infective endocarditis (IE) among those at moderate risk for IE.
Study Design: This is a case control study of oral hygiene among hospitalized patients with IE (cases) and outpatients with heart valve disease but without IE (controls). The primary outcome was the mean dental calculus index. Secondary outcomes included other measures of oral hygiene and periodontal disease (e.g., dental plaque, gingivitis) and categorization of blood culture bacterial species in case participants.
Results: The 62 case participants had 53% greater mean dental calculus index than the 119 control participants (0.84, 0.55, respectively; difference = 0.29, 95% CI: 0.11, 0.48; P = .002) and 26% greater mean dental plaque index (0.88, 0.70, respectively; difference = 0.18, 95% CI: 0.01.0.36; P = .043). Overall, cases reported fewer dentist and dental hygiene visits (P = .013) and fewer dental visits in the 12 weeks before enrollment than controls (P = .007). Common oral bacteria were identified from blood cultures in 27 of 62 cases (44%).
Conclusions: These data provide evidence to support and strengthen current American Heart Association guidance that those at risk for IE can reduce potential sources of IE-related bacteremia by maintaining optimal oral health through regular professional dental care and oral hygiene procedures.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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