Physical activity in the first postoperative week in 132 knee arthroplasty patients randomized to 3 different analgesic regimens.

Autor: Husby VS; Department of Orthopaedic Surgery, Trondheim University Hospital, Trondheim, Norway.; Department of Health Sciences Aalesund, Faculty of Medicine and Health Science, Norwegian University of Science and Technology, Aalesund, Norway., Rian T; Clinic of Anesthesia and Intensive Care, Trondheim University Hospital, Trondheim, Norway.; Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Science, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Klaksvik J; Orthopedic Research Center, Orthopaedic Department, Trondheim University Hospital, Trondheim, Norway., Wik TS; Department of Orthopaedic Surgery, Trondheim University Hospital, Trondheim, Norway.; Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Science, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Winther SB; Orthopedic Research Center, Orthopaedic Department, Trondheim University Hospital, Trondheim, Norway.
Jazyk: angličtina
Zdroj: Medicine [Medicine (Baltimore)] 2023 Apr 21; Vol. 102 (16), pp. e33471.
DOI: 10.1097/MD.0000000000033471
Abstrakt: Background: The aim of this study was to investigate whether objectively recorded physical activity in the first week after surgery in total knee arthroplasty patients differed between patients allocated to 3 different analgesic regimens.
Methods: A total of 132 total knee arthroplasty patients wore activity monitors 24 hours a day from day 1 after surgery for 6 consecutive days. The time mobilized (stepping/standing) and the number of steps were recorded. This study was a sub-study of a randomized controlled study comparing tapentadol extended-release (ER), oxycodone controlled-release (CR), or a non-opioid placebo analgesic regimen.
Results: The placebo group spent significantly more time mobilized than the tapentadol ER and the oxycodone CR groups (P = .016 and .042, respectively), but no statistically significant differences were found between the groups in the number of steps taken. The activity levels of patients in all groups increased in the first week after surgery.
Conclusion: Patients in the non-opioid placebo group spent more time mobilized the first week after surgery than those in the tapentadol ER and the oxycodone CR groups, while the number of steps was not different between the groups.
Competing Interests: The authors have no conflicts of interest to disclose.
(Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze: MEDLINE