Identifying novel biomarkers associated with bladder cancer treatment outcomes.
| Autor: | Castaneda PR; Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Theodorescu D; Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, United States., Rosser CJ; Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.; Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, United States., Ahdoot M; Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, United States. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Frontiers in oncology [Front Oncol] 2023 Mar 29; Vol. 13, pp. 1114203. Date of Electronic Publication: 2023 Mar 29 (Print Publication: 2023). |
| DOI: | 10.3389/fonc.2023.1114203 |
| Abstrakt: | Bladder cancer is a complex disease with variable prognosis. Recent investigations into the molecular landscape of bladder cancer have revealed frequent genetic alterations and molecular subtypes with therapeutic implications. Consequently, a shift toward personalized treatment of bladder cancer is underway. To this end, several biomarkers have been developed and tested in their ability to predict response to treatment in patients with bladder cancer and potentially help direct therapy. We performed a search of recently published PubMed articles using terms "biomarker," "bladder cancer," and the respective treatment discussed (i.e., "neoadjuvant" or "BCG"). In this review, we summarize the latest studies on novel biomarkers in bladder cancer with a focus on those intended to improve risk stratification and treatment selection. Competing Interests: CR is an officer of Nonagen Bioscience Corporation manufacturer of Oncuria. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Castaneda, Theodorescu, Rosser and Ahdoot.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|