Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals.
| Autor: | Kakobo PK; Department of Otorhinolaryngology, University of Kinshasa, Kinshasa, Democratic Republic of Congo., Kalala HK; Department of Otorhinolaryngology, University of Kinshasa, Kinshasa, Democratic Republic of Congo., Kelekele JK; Ophthalmology Department, University of Kinshasa, Kinshasa, Democratic Republic of Congo., Mutombo PB; School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of Congo., Nyembue DT; Department of Otorhinolaryngology, University of Kinshasa, Kinshasa, Democratic Republic of Congo., Hellings PW; Department of Otorhinolaryngology-Head and Nose Surgery, University Hospital of Leuven, Leuven, Belgium.; Department of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Upper Airways Research Laboratory, University of Ghent, Ghent, Belgium., Kayembe JN; Department of Pneumology, University of Kinshasa, Kinshasa, Democratic Republic of Congo. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in allergy [Front Allergy] 2023 Mar 22; Vol. 4, pp. 1138537. Date of Electronic Publication: 2023 Mar 22 (Print Publication: 2023). |
| DOI: | 10.3389/falgy.2023.1138537 |
| Abstrakt: | Objective: To identify the determinants of uncontrolled allergic rhinitis (UCAR) in a hospital setting in Kinshasa, Democratic Republic of Congo. Methods: Hospital-based cross-sectional study of 153 patients with allergic rhinitis (AR). The diagnosis of AR was based on clinical grounds according to the Allergic Rhinitis and its Impact on Asthma (ARIA) criteria. Categorization into controlled AR (CAR) and UCAR was based on the visual analog scale (VAS with cut off point of 5). Binary logistic regression was used to identify factors associated with UCAR. Results: Patients with UCAR (60.1%) proportionally outnumbered those with CAR (39.9%). There were significantly more patients younger than 30 years of age among patients with UCAR. Factors significantly associated with UCAR were age below 30 years (OR = 3.31; 95% CI: 1.49-7.36; p = 0.003), low serum vitamin D level (OR = 3.86; 95% CI: 1.72-8.68; p = 0.001), persistent form (OR = 3.11; 95% CI: 1.39-6.98; p = 0.006) and moderate to severe form of AR (OR = 4.31; 95% CI: 1.77-10.49; p = 0.001). Conclusions: Factors associated with UCAR in this study population were younger age less than 30 years, low vitamin D level, and persistent as well as moderate to severe AR. Further studies are needed to elucidate the underlying mechanisms favoring the occurrence of these factors. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (© 2023 Kakobo, Kalala, Kelekele, Mutombo, Nyembue, Hellings and Kayembe.) |
| Databáze: | MEDLINE |
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