Congenital Infantile Myofibroma: The Importance of Molecular Diagnosis.
| Autor: | Machado Morais J; Pediatrics, Hospital Pedro Hispano, Porto, PRT., Castro C; Pediatrics, Hospital Pedro Hispano, Porto, PRT., Ferraz C; Pediatrics and Neonatology, Hospital Pedro Hispano, Porto, PRT., Lima J; Molecular Biology, Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, PRT., Barroca H; Anatomic Pathology, Centro Hospitalar Universitário São João, Porto, PRT., Bom-Sucesso M; Pediatric Oncology, Centro Hospitalar Universitário São João, Porto, PRT. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Mar 08; Vol. 15 (3), pp. e35885. Date of Electronic Publication: 2023 Mar 08 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.35885 |
| Abstrakt: | Infantile myofibromatosis is an uncommon soft tissue neoplasm that may present at birth or in early infancy. Although rare, this neoplasm is one of the most common benign fibrous tumors of infancy. Even though these tumors do not spread, they can compress or damage nearby organs. There is not an established management protocol, but it is advisable to maintain periodic clinical and imagological control until stability. Watchful waiting is an option to consider in the absence of problematic symptoms and visceral involvement. We report a case of solitary infantile myofibromatosis, without visceral involvement. It showed an initial rapid growth, raising concern among medical doctors and motivating soft tissue biopsy, always recommended as the clinical picture deviates from the classic presentation. Histology interpretation is often challenging, making genetics and clinical evaluation essential to exclude and prevent the misdiagnosing of more aggressive lesions. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Machado Morais et al.) |
| Databáze: | MEDLINE |
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