Impact of smoking on nasal mucociliary clearance time in Kano metropolis, Nigeria.

Autor: Mahmud A; Department of ENT Federal Medical Centre Yola Yola Nigeria.; Department of ENT Aminu Kano Teaching Hospital Kano Nigeria., Salisu AD; Department of ENT, Aminu Kano Teaching Hospital Bayero University Kano Kano Nigeria., Kolo ES; Department of ENT, Aminu Kano Teaching Hospital Bayero University Kano Kano Nigeria., Hasheem MG; Department of ENT, Aminu Kano Teaching Hospital Bayero University Kano Kano Nigeria., Bello-Muhammad N; Department of ENT, Aminu Kano Teaching Hospital Bayero University Kano Kano Nigeria., Tukur AR; Department of ENT, Aminu Kano Teaching Hospital Bayero University Kano Kano Nigeria., Nuhu YJ; Department of ENT, Aminu Kano Teaching Hospital Bayero University Kano Kano Nigeria., Jalo RI; Department of ENT, Aminu Kano Teaching Hospital Bayero University Kano Kano Nigeria.; Department of Community Medicine Aminu Kano Teaching Hospital/Bayero University Kano Kano Nigeria.
Jazyk: angličtina
Zdroj: World journal of otorhinolaryngology - head and neck surgery [World J Otorhinolaryngol Head Neck Surg] 2022 Apr 18; Vol. 9 (1), pp. 53-58. Date of Electronic Publication: 2022 Apr 18 (Print Publication: 2023).
DOI: 10.1002/wjo2.61
Abstrakt: Background: Mucociliary clearance is an important defense mechanism in human upper and lower respiratory airways. Impairment of this process by certain conditions such as cigarette smoking can predispose to chronic infection and neoplasm of the nose and paranasal sinuses.
Methods: This was a cross-sectional study conducted in Kano metropolis, Nigeria. Eligible adults were enrolled, a saccharine test was conducted, and the nasal mucociliary clearance time was assessed. Analysis of the result was carried out using Statistical Product and Service Solutions version 23.0.
Results: There were 225 participants categorized into 75 active smokers (33.3%), 74 passive smokers (32.9%), and 76 nonsmokers (33.8%, living in a smoking-free zone). The age range of the participants was between 18 and 50 years, with a mean age of (31.2 ± 5.6) years. All participants were males. There were 139 (61.8%) of Hausa-Fulani ethnic group, 24 (10.7%) Yoruba, 18 (8.0%) Igbo, and 44 (19.5%) other ethnic groups. Findings in this study showed that the average mucociliary clearance time among active smokers was prolonged ([15.25 ± 6.20] min) compared to passive ([11.41 ± 4.25] min) and nonsmokers ([9.17 ± 2.76] min) respectively, with a statistical significance ( F  = 33.59, P  < 0.001). Binary logistic regression revealed that the number of cigarettes smoked per day was an independent predictor of prolonged mucociliary clearance time ( P  = 0.008, odds ratio = 0.44, 95% confidence interval = 0.24-0.80).
Conclusion: Active cigarette smoking is associated with prolonged nasal mucociliary clearance time. The number of cigarette sticks smoked per day was found to be an independent predictor of prolonged mucociliary clearance time.
Competing Interests: The authors declare no conflicts of interest.
(© 2022 The Authors. World Journal of Otorhinolaryngology ‐ Head and Neck Surgery published by John Wiley & Sons Ltd on behalf of Chinese Medical Association.)
Databáze: MEDLINE
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