Nightmares: an independent risk factor for cardiovascular disease?

Autor:	Campbell AA; Durham Veterans Affairs (VA) Healthcare System, Durham, NC, USA., Taylor KA; Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.; Duke University School of Medicine, Duke Clinical Research Institute, Durham, NC, USA., Augustine AV; Durham Veterans Affairs (VA) Healthcare System, Durham, NC, USA.; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA., Sherwood A; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA., Wu JQ; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA., Beckham JC; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.; Veterans Affairs VA Mid-Atlantic MIRECC Workgroup, Durham, NC, USA., Hoerle JM; Veterans Affairs VA Mid-Atlantic MIRECC Workgroup, Durham, NC, USA., Ulmer CS; Durham Veterans Affairs (VA) Healthcare System, Durham, NC, USA.; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.; Durham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Jazyk:	angličtina
Zdroj:	Sleep [Sleep] 2023 Jun 13; Vol. 46 (6).
DOI:	10.1093/sleep/zsad089
Abstrakt:	Study Objectives: Prior work has established associations between post-traumatic stress disorder (PTSD), disrupted sleep, and cardiovascular disease (CVD), but few studies have examined health correlates of nightmares beyond risks conferred by PTSD. This study examined associations between nightmares and CVD in military veterans. Methods: Participants were veterans (N = 3468; 77% male) serving since September 11, 2001, aged 38 years (SD = 10.4); approximately 30% were diagnosed with PTSD. Nightmare frequency and severity were assessed using the Davidson Trauma Scale (DTS). Self-reported medical issues were assessed using the National Vietnam Veterans Readjustment Study Self-report Medical Questionnaire. Mental health disorders were established using the Structured Clinical Interview for DSM-IV. The sample was stratified by the presence or absence of PTSD. Within-group associations between nightmare frequency and severity and self-reported CVD conditions, adjusting for age, sex, race, current smoking, depression, and sleep duration. Results: Frequent and severe nightmares during the past week were endorsed by 32% and 35% of participants, respectively. Those endorsing nightmares that were frequent, severe, and the combination thereof were more likely to also evidence high blood pressure (ORs 1.42, OR 1.56, and OR 1.47, respectively) and heart problems (OR 1.43, OR 1.48, and OR 1.59, respectively) after adjusting for PTSD diagnosis and other covariates. Conclusions: Nightmare frequency and severity among veterans are associated with cardiovascular conditions, even after controlling for PTSD diagnosis. Study findings suggest that nightmares may be an independent risk factor for CVD. Additional research is needed to validate these findings using confirmed diagnoses and explore potential mechanisms. (Published by Oxford University Press on behalf of Sleep Research Society (SRS) 2023.)
Databáze:	MEDLINE
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