Spectrum of cutaneous granulomatous lesions: A 5-year experience in a tertiary care centre in Sarawak.

Autor: Ting IPL; Sarawak General Hospital, Dermatology Department, Kuching, Sarawak, Malaysia. ingrid_tpl15@hotmail.com., Tan HZ; Sarawak General Hospital, Dermatology Department, Kuching, Sarawak, Malaysia., Teo HG; Sarawak General Hospital, Dermatology Department, Kuching, Sarawak, Malaysia., Kiing JW; Sarawak General Hospital, Dermatology Department, Kuching, Sarawak, Malaysia., Muniandy P; Sarawak General Hospital, Dermatology Department, Kuching, Sarawak, Malaysia.
Jazyk: angličtina
Zdroj: The Medical journal of Malaysia [Med J Malaysia] 2023 Mar; Vol. 78 (2), pp. 184-189.
Abstrakt: Introduction: Granulomatous skin lesions can have various histopathological features leading to diagnostic confusion. The study aimed to determine the frequency and pattern of different granulomatous skin lesions.
Materials and Methods: This was a 5-year retrospective study done between April 2017 and March 2022 at Dermatology Department, Sarawak General Hospital. Subjects with a clinicopathological diagnosis of granulomatous diseases were included in the analysis.
Results: A total of 1718 skin biopsies were done during the study periods, with 49 (2.8%) confirmed granulomatous skin lesions. Most patients were aged 40-60 with a male predominance of 51%. Most of the skin biopsy samples were taken from the upper limb (36%). In this study, epitheloid granuloma was the commonest subtype (21, 43%) followed by suppurative granuloma (12, 24%), tuberculoid granuloma (8, 16%) and foreign body granuloma (5, 10%). The commonest aetiology of granulomatous skin lesions in our study was infections (30, 61%) followed by foreign body inoculation (8, 16%). Fungal infection was the most common infective cause, followed by cutaneous tuberculosis.
Conclusion: The major cause of granulomatous dermatoses in developing countries is still infections, fungal and tuberculosis being the leading causes.
Databáze: MEDLINE
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