[Frequency of clinical characteristics and factors associated with mortality in patients hospitalized for COVID-19 in Puebla, Mexico].

Autor: Hernández-Morales MDR; Servicio de Inmunología Clínica y Alergia. ciaic.puebla@gmail.com., Maldonado-Castañeda S; Área de Investigación y Enseñanza. Hospital General Dr. Eduardo Vázquez N, Puebla, México., Mancilla-Hernández E; Centro de Investigación en el Área de la Salud, Puebla, México., Amaro-Zarate I; Hospital General de Huejotzingo, Secretaria de Salud del Estado de Puebla, México., Aguirre-Barbosa M; Hospital General 'Dr. Eduardo Vázquez N'. Secretaria de Salud del Estado de Puebla., Nazarala-Sanchez S; Hospital General 'Dr. Eduardo Vázquez N'. Secretaria de Salud del Estado de Puebla.
Jazyk: Spanish; Castilian
Zdroj: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) [Rev Alerg Mex] 2023 Jan 04; Vol. 69 (2), pp. 67-71. Date of Electronic Publication: 2023 Jan 04.
DOI: 10.29262/ram.v69i2.1146
Abstrakt: Background: Mexico has a very high mortality rate from COVID19, risk factors, clinical manifestations of our population are unknown.
Objective: To know risk factors for mortality from COVID19 in hospitalized patients of the Secretary of Health (SSA) Puebla, and clinical characteristics.
Material and Methods: Case-control, observational, retrospective, cross-sectional study in COVID-19 patients. 2 groups: COVID-19 patients who died and those who did not die.
Results: 502  patients,  314  men  (62.5%  CI95%  58-66%),  188  women  (37.5%  CI95%  33-42%),  mean  age  54.14  +13.8,  interquartile  range  (IQR)  45-63, age interval 19 and 90 years, hospital stay (DEIH) 1-43 days, mean 9.8+7.8 days, median 8, IQR 4-13 days. Symptoms associated with mortality: dyspnea, chest pain, MR>1. Variables associated with mortality: age = or > 65 years, greater IHD, having > 2 comorbidities (OR 1.453), diabetes (OR 1.759), hypertension (OR 6.29) and chronic kidney failure (CRF) (OR 3.16) , (p<0.05). Ferritin >500ng/ml (OR 5.1799), DHL >400 IU/L (OR 3.313) and D-dimer >2000 m/ml (OR 2.868).
Conclusions: Age > or = 65 years, greater IHD, > 2 comorbidities, diabetes, hypertension or CRF, increased ferritin, D-dimer or DHL, are risk factors for mortality from COVID-19.
Databáze: MEDLINE
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