A 16-month-long experience of COVID-19 in allogeneic haematopoietic stem cell transplantation recipients: An SFGM-TC multicentre cohort study.

Autor: Xhaard A; Service d'hématologie-Greffe, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, Paris, France., Xhaard C; INSERM, Centre d'Investigations Cliniques Plurithématique 1433, INSERM 1116, CHRU de Nancy, FCRIN INI-CRCT, Université de Lorraine, Nancy, France., Rubio MT; Service d'hématologie, Hôpital Brabois, CHRU Nancy et CNRS UMR 7563, Biopôle de l'Université de Lorraine, Vandoeuvre les Nancy, France., Berceanu A; Service d'hématologie, CHU Jean Minjoz, Besançon, France., Botella-Garcia C; Service d'hématologie, CHU Bordeaux, Bordeaux, France., Coman T; Service d'hématologie, Institut Gustave Roussy, Villejuif, France., Tavernier E; Département d'hématologie Clinique et de Thérapie Cellulaire, CHU Saint-Etienne, Saint-Etienne, France., Labussière-Wallet H; Service d'hématologie, Hôpital Lyon Sud, Pierre Bénite Cedex, France., Chevallier P; Service d'hématologie, CHU, Nantes, France., Legrand F; Département d'hématologie, Institut Paoli-Calmettes, Marseille, France., Thiebaut A; Service d'hématologie, CHU Grenoble, Grenoble, France., Menard AL; Service d'hématologie, CHU Rouen, Rouen, France., Paillard C; Service d'hématologie pédiatrique, CHRU Strasbourg, Strasbourg, France., Chantepie S; Service d'hématologie, CHU Caen, Caen, France., Robin M; Service d'hématologie-Greffe, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, Paris, France., Nguyen S; Service d'hématologie Sorbonne Université, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Jazyk: angličtina
Zdroj: British journal of haematology [Br J Haematol] 2023 Jun; Vol. 201 (6), pp. 1066-1071. Date of Electronic Publication: 2023 Mar 15.
DOI: 10.1111/bjh.18754
Abstrakt: This 16-month-long multicentre retrospective study of 225 allogeneic haematopoietic stem cell transplantation (alloHSCT) recipients with COVID-19 examines risk factors for severity and mortality, describing the successive waves of infections (from March to June 2020 and from August 2020 to June 2021). We confirm the negative role of low respiratory tract disease and immunosuppressive treatment. We highlight significantly lower percentages of severe forms and COVID-19-related mortality during the second wave. Monthly comparative evolution of cases in alloHSCT recipients and in the French population shows a higher number of cases in alloHSCT recipients during the first wave and a decrease from February 2021.
(© 2023 British Society for Haematology and John Wiley & Sons Ltd.)
Databáze: MEDLINE
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