Prevalence and Clinical Relevance of Schistosoma mansoni Co-Infection with Mycobacterium tuberculosis : A Systematic Literature Review.

Autor:	Baya B; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.; Service of Pneumopthisiology of the University Teaching Hospital of Point G, Bamako, Mali., Kone B; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Somboro A; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Kodio O; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Somboro AM; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Diarra B; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Traore FG; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Kone D; Clinical Laboratory of the University Teaching Hospital of Point G, Bamako, Mali., Traore MA; Clinical Laboratory of the University Teaching Hospital of Point G, Bamako, Mali., Kone M; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Togo AG; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Sarro YS; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Maiga A; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Maiga M; Clinical Laboratory of the University Teaching Hospital of Point G, Bamako, Mali.; Havey Institute for Global Health (Havey IGH), Northwestern University (NU), Chicago, USA., Toloba Y; Service of Pneumopthisiology of the University Teaching Hospital of Point G, Bamako, Mali., Diallo S; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali., Murphy RL; Havey Institute for Global Health (Havey IGH), Northwestern University (NU), Chicago, USA., Doumbia S; University Clinical Research Center (UCRC) of the University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.
Jazyk:	angličtina
Zdroj:	Open journal of epidemiology [Open J Epidemiol] 2023 Feb; Vol. 13 (1), pp. 97-111. Date of Electronic Publication: 2023 Feb 23.
DOI:	10.4236/ojepi.2023.131008
Abstrakt:	Tuberculosis disease stands for the second leading cause of death worldwide after COVID-19, most active tuberculosis cases result from the reactivation of latent TB infection through impairment of immune response. Several factors are known to sustain that process. Schistosoma mansoni , a parasite of the helminth genus that possesses switching power from an immune profile type Th1 to Th2 that favors reactivation of latent TB bacteria. The aim of the study was to assess the prevalence of the co-infection between the two endemic infections. Systematic literature was contacted at the University Clinical Research Center at the University of Sciences, Techniques, and Technologies of Bamako in Mali. Original articles were included, and full texts were reviewed to assess the prevalence and better understand the immunological changes that occur during the co-infection. In total, 3530 original articles were retrieved through database search, 53 were included in the qualitative analysis, and data from 10 were included in the meta-analysis. Prevalence of the co-infection ranged from 4% to 34% in the literature. Most of the articles reported that immunity against infection with helminth parasite and more specifically Schistosoma mansoni infection enhances latent TB reactivation through Th1/Th2. In sum, the impact of Schistosoma mansoni co-infection with Mycobacterium tuberculosis is under-investigated. Understanding the role of this endemic tropical parasite as a contributing factor to TB epidemiology and burden could help integrate its elimination as one of the strategies to achieve the END-TB objectives by the year 2035. Competing Interests: Conflicts of Interest The authors declare no conflicts of interest regarding the publication of this paper.
Databáze:	MEDLINE
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