Study protocol for approach bias retraining for nicotine addiction among dual combustible and electronic cigarette users.

Autor: Clausen B; Department of Psychology, University of Houston, Houston, TX, United States of America., Rinck M; Behavioral Science Institute, Radboud University, Nijmegen, the Netherlands., Nizio P; Department of Psychology, University of Houston, Houston, TX, United States of America; HEALTH Institute, University of Houston, Houston, TX, United States of America., Matoska CT; Department of Psychology, University of Houston, Houston, TX, United States of America., Zappi C; Department of Psychology, University of Houston, Houston, TX, United States of America., Smits JAJ; Department of Psychology, University of Texas at Austin, Austin, TX, United States of America., Gallagher MW; Department of Psychology, University of Houston, Houston, TX, United States of America., Zvolensky MJ; Department of Psychology, University of Houston, Houston, TX, United States of America; HEALTH Institute, University of Houston, Houston, TX, United States of America; Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America., Garey L; Department of Psychology, University of Houston, Houston, TX, United States of America. Electronic address: llgarey@uh.edu.
Jazyk: angličtina
Zdroj: Contemporary clinical trials [Contemp Clin Trials] 2023 May; Vol. 128, pp. 107145. Date of Electronic Publication: 2023 Mar 09.
DOI: 10.1016/j.cct.2023.107145
Abstrakt: Background: Electronic cigarette (ECIG) use has become a popular method for nicotine delivery. Combustible cigarette (CC) cessation or reduction are the primary reasons for ECIG uptake among adults. Yet, most CC smokers who initiate ECIG use do not fully transition from CC to ECIG, despite intending to quit CC completely. Retraining approach bias, or the approach action tendency toward stimuli related to the substance of interest, has been effective in alcohol and CC use treatments. However, approach bias retraining for both CC and (ECIG) users has not been explored. Therefore, the objective of the study is to evaluate the initial efficacy of approach bias retraining among dual CC and ECIG users.
Methods: Eligible dual CC/ECIG using adults (N = 90) will complete a phone-screener, baseline assessment, 4 treatment sessions over 2 weeks, ecological momentary assessments (EMAs) post-intervention, and follow-ups at 4- and 6-week post-intervention. Participants will be assigned to one of three conditions at baseline: (1) CC + ECIG retraining; (2) CC only retraining; and (3) sham retraining. Participants will engage in a self-guided quit attempt to abstain from all nicotine products starting at treatment session 4.
Conclusions: The study may lead to a more effective treatment for at-risk nicotine users while simultaneously isolating explanatory mechanisms. The findings should guide advances in the theoretical conceptualization of nicotine addiction for dual users and mechanisms involved in maintaining and abstaining from CC and ECIG, and provide initial effect size data for a brief intervention, thus providing necessary data for a large-scale follow-up trial. Clinical Trials ID: NCT05306158.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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