Effect of Obesity on Clinical Outcomes in COVID-19 Patients.

Autor:	Habis Y; Division of Pulmonology, Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Alsilmi R; Division of Pulmonology, Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Alirbidi L; Department of Medicine and Surgery, Faculty of Medicine, King Abdulaziz University, Rabigh, SAU., Safhi M; Department of Medicine, King Abdulaziz University Hospital, Jeddah, SAU., Alsallum F; Department of Medicine, King Faisal Specialist Hospital and Research Centre, Jeddah, SAU., Alharbi R; Department of Medicine, East Jeddah General Hospital, Jeddah, SAU., Samman A; Department of Medicine, King Faisal Specialist Hospital and Research Centre, Jeddah, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Jan 13; Vol. 15 (1), pp. e33734. Date of Electronic Publication: 2023 Jan 13 (Print Publication: 2023).
DOI:	10.7759/cureus.33734
Abstrakt:	Background Obesity is a well-known risk factor for developing severe coronavirus disease 2019 (COVID-19). In this study, we sought to determine the relationship between obesity and poor outcomes in patients with COVID-19 patients at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia. Methods We conducted a single-centered descriptive study of adult COVID-19 patients hospitalized between March 1 and December 31, 2020, at KAUH. Patients were classified according to body mass index (BMI) as overweight (BMI 25-29.9 kg/m 2 ) or obese (BMI ≥30 kg/m 2 ). The main outcomes were admission to the intensive care unit (ICU), intubation, and death. Results Data were analyzed from 300 COVID-19 patients. Most study participants were overweight (61.8%), and 38.2% were obese. The most significant comorbidities were diabetes (46.8%) and hypertension (41.9%). Both hospital mortality (10.4% for obese; 3.8% for overweight, p = 0.021) and intubation rates (34.6% for obese; 22.7% for overweight, p = 0.004) were significantly higher among obese patients than overweight patients. There was no significant difference in terms of ICU admission rate between both groups. However, intubation rates (34.6% for obese; 22.7% for overweight, p = 0.004) and hospital mortality (10.4% for obese; 3.8% for overweight, p = 0.021) were significantly higher among obese patients than overweight patients. Conclusions This study aimed to describe the effect of high BMI on the clinical outcome of COVID-19 patients in Saudi Arabia. Obesity is significantly correlated with poor clinical outcomes in COVID-19. It is also associated with higher mortality and the need for mechanical ventilation necessitating intensive care unit admission. Patients with higher BMI should be prioritized in the hospital setting, as they have a higher potential of developing severe COVID-19 complications and sequelae. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Habis et al.)
Databáze:	MEDLINE
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