Handgrip strength is associated with 12-month survival in male patients suffering with advanced chronic liver disease.

Autor: Côrtes DM; Post Graduate Program, School of Nutrition, Federal University of Bahia, Salvador, Bahia, Brazil., Boulhosa RSDSB; Post Graduate Program, School of Nutrition, Federal University of Bahia, Salvador, Bahia, Brazil., L da S L Paz C; Bahia Social College, Salvador, Bahia, Brazil., Cunha CM; Science Nutrition Department, Federal University of Bahia, Salvador, Bahia, Brazil.; Food, Nutrition and Health Post-Graduation Program, Federal University of Bahia, Salvador, Bahia, Brazil., de Oliveira LPM; Science Nutrition Department, Federal University of Bahia, Salvador, Bahia, Brazil.; Food, Nutrition and Health Post-Graduation Program, Federal University of Bahia, Salvador, Bahia, Brazil., Lyra AC; Department of Gastroenterology, Federal University of Bahia, Salvador, Bahia, Brazil., Bueno AA; College of Health, Life and Environmental Sciences, University of Worcester, Worcester, UK., de Jesus RP; Science Nutrition Department, Federal University of Bahia, Salvador, Bahia, Brazil.; Food, Nutrition and Health Post-Graduation Program, Federal University of Bahia, Salvador, Bahia, Brazil.
Jazyk: angličtina
Zdroj: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association [J Hum Nutr Diet] 2023 Aug; Vol. 36 (4), pp. 1170-1178. Date of Electronic Publication: 2023 Mar 13.
DOI: 10.1111/jhn.13160
Abstrakt: Background: Advanced chronic liver disease (ACLD) patients are usually malnourished, and both conditions in combination increase the likelihood of unfavourable clinical outcomes. Handgrip strength (HGS) has been suggested as a relevant parameter for nutritional assessment and predictor of adverse clinical outcomes in ACLD. However, the HGS cut-off values for ACLD patients have not yet been reliably established. The aims of this study were to preliminarily identify HGS reference values in a sample population of ACLD male patients and to assess their association with survival over a 12-month follow-up period.
Methods: This was a prospective observational study with preliminary analysis of outpatients and inpatients. A total of 185 male patients with a medical diagnosis of ACLD met the inclusion criteria and were invited to participate in the study. The physiological variation in muscle strength related to the age of the individuals included in the study was considered to obtain cut-off values.
Results: After categorising HGS by age group (adults: 18-60 years; elderly: ≥60 years), the reference values obtained were 32.5 kg for the adults and 16.5 kg for the elderly. During the 12-month follow-up, 20.5% of the patients died, and 76.3% of those had been identified with reduced HGS.
Conclusions: Patients with adequate HGS showed significantly higher 12-month survival than those with reduced HGS within the same period. Our findings show that HGS is an important predictive parameter for clinical and nutritional follow-up in ACLD male patients.
(© 2023 The British Dietetic Association Ltd.)
Databáze: MEDLINE
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