Histopathological study of experimentally induced endolymphatic hydrops with emphasis on Reissner's membrane.

Autor: Ruding PR; Department of Otorhinolaryngology, University Hospital, Utrecht, The Netherlands., Veldman JE, van Deelen GW, Smoorenburg GF, Huizing EH
Jazyk: angličtina
Zdroj: Archives of oto-rhino-laryngology [Arch Otorhinolaryngol] 1987; Vol. 244 (3), pp. 174-9.
DOI: 10.1007/BF00464263
Abstrakt: We investigated the histopathological changes of the guinea pig cochlea in experimentally induced endolymphatic hydrops 1, 2, 4 and 8 months after obliteration of the endolymphatic sac. In this paper special attention is given to the morphological changes created in Reissner's membrane. Reissner's membrane showed various foldings, bony wall connections, local thickenings, duplications, mesothelial defects, ruptures and atrophy. The incidence of these changes increased with survival time. The stria vascularis and hair cells showed degeneration starting apically and proceeding towards the cochlear base. The possible implications of these findings are discussed.
Databáze: MEDLINE