JMM Profile: Swine influenza A virus: a neglected virus with pandemic potential.

Autor:	Mollett BC; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., Everett HE; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., van Diemen PM; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., Byrne AMP; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., Ramsay A; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., James J; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; WOAH/FAO International Reference Laboratory for Avian Influenza and Swine Influenza, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., Reid SM; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., Hansen RDE; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., Lewis NS; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; WOAH/FAO International Reference Laboratory for Avian Influenza and Swine Influenza, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; Department of Pathobiology and Population Sciences, Royal Veterinary College,, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK.; Present address: Worldwide Influenza Centre, WHO Collaborating Centre for Reference and Research on Influenza, The Francis Crick Institute, London, NW1 1AT, 1 Midland Road, UK., Brown IH; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; WOAH/FAO International Reference Laboratory for Avian Influenza and Swine Influenza, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK., Banyard AC; Department of Virology, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; WOAH/FAO International Reference Laboratory for Avian Influenza and Swine Influenza, Animal and Plant Health Agency (APHA), Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; Institute for Infection and Immunity, St George's Hospital Medical School, University of London, London SW17 0RE, UK.
Jazyk:	angličtina
Zdroj:	Journal of medical microbiology [J Med Microbiol] 2023 Jan; Vol. 72 (1).
DOI:	10.1099/jmm.0.001623
Abstrakt:	Swine influenza is an acute respiratory disease of swine caused by swine influenza A virus (SwIAV). The ability of SwIAV to spread bidirectionally from animals to humans (zoonotic), and from humans to animals (reverse zoonotic), drives coinfection that can result in gene segment exchange and elevates the risk of generating viruses with pandemic potential. Compared to human-origin influenza A viruses, current data indicate a greater diversity amongst circulating SwIAVs, with three major subtypes (classified by haemagglutinin and neuraminidase) circulating globally in swine (H1N1, H1N2 and H3N2). The lack of protection afforded by human seasonal influenza vaccines against SwIAVs exacerbates the risk associated with reassortment of human, swine and potentially avian viruses. As such, global monitoring of SwIAVs is important for both human and animal health as they represent a true 'One Health' challenge with pandemic potential.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu