Shared grey matter correlates of reading and attention.

Autor: Lee MM; Department of Psychology, American University, United States; Department of Neuroscience, American University, United States., Drury BC; Undergraduate Program in Neuroscience, American University, United States., McGrath LM; Department of Psychology, University of Denver, United States., Stoodley CJ; Department of Psychology, American University, United States; Department of Neuroscience, American University, United States. Electronic address: stoodley@american.edu.
Jazyk: angličtina
Zdroj: Brain and language [Brain Lang] 2023 Feb; Vol. 237, pp. 105230. Date of Electronic Publication: 2023 Feb 01.
DOI: 10.1016/j.bandl.2023.105230
Abstrakt: Disorders of reading (developmental dyslexia) and attention (ADHD) have a high rate of comorbidity (25-40%), yet little is known about the neural underpinnings of this phenomenon. The current study investigated the shared and unique neural correlates of reading and attention in 330 typically developing children ages 8-18 from the Philadelphia Neurodevelopmental Cohort. Multiple regression analyses were used to identify regions of the brain where grey matter (GM) volume was associated with reading or attention scores (p < 0.001, cluster FDR p < 0.05). Better attention scores correlated with increased GM in the precuneus and higher reading scores were associated with greater thalamic GM. An exploratory conjunction analysis (p < 0.05, k > 239) found that GM in the caudate and precuneus correlated with both reading and attention scores. These results are consistent with a recent meta-analysis which identified GM reductions in the caudate in both dyslexia and ADHD and reveal potential shared neural correlates of reading and attention.
Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Marissa Lee – none. Brianne Drury – none. Catherine Stoodley – none. Lauren McGrath - receives royalties from the textbook Diagnosing Learning Disorders: From Science into Practice, 3rd Edition from Guilford Press.
(Copyright © 2023. Published by Elsevier Inc.)
Databáze: MEDLINE
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