Sialylation of IgE reduces FcεRIα interaction and mast cell and basophil activation in vitro and increases IgE half-life in vivo.

Autor: Dühring L; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Petry J; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Lilienthal GM; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Bartsch YC; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Kubiak M; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Pfeufer C; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Lehrian S; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Buhre JS; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Lunding HB; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Kern C; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany., Behrends J; Core Facility Fluorescence Cytometry, Research Center Borstel, Leibniz Lung Center, Borstel, Germany., Walsemann T; Division of Clinical and Molecular Allergology, Priority Area Chronic Lung Diseases, Research Center Borstel, Leibniz Lung Center, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Borstel, Germany., Gädert L; Fraunhofer Institute of Toxicology and Experimental Medicine, German Center for Lung Research (DZL), Hannover, Germany., Sommer C; Fraunhofer Institute of Toxicology and Experimental Medicine, German Center for Lung Research (DZL), Hannover, Germany., Krüger L; Department of Human Medicine, Medical School Berlin, Berlin, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Blanchard V; Department of Human Medicine, Medical School Berlin, Berlin, Germany.; Institute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Dehmel S; Fraunhofer Institute of Toxicology and Experimental Medicine, German Center for Lung Research (DZL), Hannover, Germany., Jappe U; Division of Clinical and Molecular Allergology, Priority Area Chronic Lung Diseases, Research Center Borstel, Leibniz Lung Center, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Borstel, Germany.; Interdisciplinary Allergy Outpatient Clinic, Department of Pneumology, University of Lübeck, Lübeck, Germany., Rahmöller J; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany.; Department of Anesthesiology and Intensive Care, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Ehlers M; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Hospital Schleswig-Holstein, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Lübeck, Germany.
Jazyk: angličtina
Zdroj: Allergy [Allergy] 2023 Aug; Vol. 78 (8), pp. 2301-2305. Date of Electronic Publication: 2023 Feb 13.
DOI: 10.1111/all.15665
Databáze: MEDLINE