Facial processing in bipolar disorder is mediated by clinical and biological aspects.

Autor: Shoshina II; Department of Liberal Arts and Sciences, St. Petersburg State University, Saint-Petersburg, Russia., Oliveira ME; Departamento de Psicologia, Universidade Federal da Paraíba (UFPB), João Pessoa, PB, Brazil. Laboratório de Percepção, Neurociências e Comportamento, UFPB, João Pessoa, PB, Brazil., Silva GM; Departamento de Psicologia, Universidade Federal da Paraíba (UFPB), João Pessoa, PB, Brazil. Laboratório de Percepção, Neurociências e Comportamento, UFPB, João Pessoa, PB, Brazil., Negreiros NS; Departamento de Psicologia, Universidade Federal da Paraíba (UFPB), João Pessoa, PB, Brazil. Laboratório de Percepção, Neurociências e Comportamento, UFPB, João Pessoa, PB, Brazil., Felisberti FM; Department of Psychology, Kingston University London, London, UK., Fernandes TP; Departamento de Psicologia, Universidade Federal da Paraíba (UFPB), João Pessoa, PB, Brazil. Laboratório de Percepção, Neurociências e Comportamento, UFPB, João Pessoa, PB, Brazil., Santos NA; Departamento de Psicologia, Universidade Federal da Paraíba (UFPB), João Pessoa, PB, Brazil. Laboratório de Percepção, Neurociências e Comportamento, UFPB, João Pessoa, PB, Brazil.
Jazyk: angličtina
Zdroj: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) [Braz J Psychiatry] 2022 Oct 07; Vol. 44 (6), pp. 602-610. Date of Electronic Publication: 2022 Oct 07.
DOI: 10.47626/1516-4446-2022-2490
Abstrakt: Objective: The process of detecting faces can be considered one of the initial steps in face recognition, which is essential for human interaction. We sought to investigate whether a face perception task reliably detects subtle perceptual disturbances between patients with bipolar disorder (BD) and healthy controls.
Methods: In this multisite study, we examined differences between BD patients and matched healthy controls. Participants were instructed to detect the orientation (either left or right) of a face when it was presented as a face/non-face pair on a computer screen using Bayesian entropy estimation. Data analyses compared performance between the groups.
Results: Overall, BD patients exhibited more perceptual disturbances compared with controls. BD patients who took olanzapine had better performance and faster reaction times (RTs) than patients who took lithium or were medication-naive. BD patients who took lithium had better performance and faster RTs than medication-naive patients. The medication-naive BD group exhibited greater disturbances than all other groups.
Conclusion: These findings highlight the reliability of the face perception task used herein and may be important for public health initiatives and follow-up studies that seek to understand the diverse effects of other variables that can affect sensory processing in this population.
Competing Interests: The authors report no conflicts of interest.
Databáze: MEDLINE
Externí odkaz: