Evaluation of the Performance of ACR TI-RADS Also Considering Those Nodules with No Indication of FNAC: A Single-Center Experience.

Autor: Amendola S; Division of Endocrinology and Diabetes, CTO Andrea Alesini Hospital, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy., Wolde Sellasie S; Division of Endocrinology and Diabetes, CTO Andrea Alesini Hospital, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy., Pedicini F; Thyroid Endocrine Surgery, Sant'Eugenio Hospital, 00144 Rome, Italy., Carlini M; Thyroid Endocrine Surgery, Sant'Eugenio Hospital, 00144 Rome, Italy., Russo G; Thyroid Endocrine Surgery, Sant'Eugenio Hospital, 00144 Rome, Italy., Ossola N; Servizio di Nutrizione Clinica e Dietetica, Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland., Leoncini A; Servizio di Radiologia e Radiologia Interventistica, Istituto di Imaging Della Svizzera Italiana (IIMSI), Ente Ospedaliero Cantonale (EOC), 6900 Lugano, Switzerland., Botti F; Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.; UOSD Anatomia Patologica Sant'Eugenio Hospital, 00144 Rome, Italy., Bonanno E; UOSD Anatomia Patologica Sant'Eugenio Hospital, 00144 Rome, Italy.; Department of Experimental Medicine, University of Rome 'Tor Vergata', Via Montpellier, 1, 00133 Rome, Italy., Trimboli P; Servizio di Endocrinologia e Diabetologia, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), 6900 Lugano, Switzerland.; Facoltà di Scienze Biomediche, Università Della Svizzera Italiana (USI), 6900 Lugano, Switzerland., Uccioli L; Division of Endocrinology and Diabetes, CTO Andrea Alesini Hospital, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2023 Jan 04; Vol. 12 (2). Date of Electronic Publication: 2023 Jan 04.
DOI: 10.3390/jcm12020398
Abstrakt: Background: Several US risk stratification score systems (RSSs) have been developed to standardize a thyroid nodule risk of malignancy. It is still a matter of debate which RSS is the most reliable. The purpose of this study is to evaluate: (1) the concordance between the American College of Radiology TI-RADS (ACR TI-RADS) and fine needle aspiration cytology (FNAC), (2) the cancer rate in the ACR TI-RADS categories, (3) the characteristics of nodules evaluated by FNAC even if not formally indicated according to ACR TI-RADS ('not indicated FNACs").
Methods: From January 2021 to September 2022, patients attending the Endocrinology Unit of the CTO Hospital of Rome for evaluation of thyroid nodules were included.
Results: 830 nodules had negative cytology, belonging to TIR2 and TIR1C. One hundred and thirteen nodules were determined to be suspicious for or consistent with malignancy belonging to TIR3B/TIR4/TIR5. Of this last group, 94% were classified as TR4/TR5 nodules. In total, 87/113 underwent surgery. Among these, 73 had histologically proven cancer, 14 turned out to be benign. "Not indicated FNACs" was 623. Among these, 42 cancers were present.
Conclusions: This study confirmed the diagnostic power of ACR TI-RADS. In addition, these data suggest revising the ACR TI-RADS indication to FNAC, especially for TR4.
Databáze: MEDLINE
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