Conduction system disorders and electrocardiographic findings in COVID-19 deceased patients in 2021, Shiraz, Iran.

Autor: Nikoo MH; Non-communicable Diseases Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran., Sadeghi A; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran., Estedlal A; Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran., Fereidooni R; Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran., Dehdari Ebrahimi N; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran., Maktabi A; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran., Kamgar M; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran., Mehran F; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran., Mehdibeygi O; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran., Esfandiari H; Non-communicable Diseases Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran., Taherinezhad Tayebi M; Non-communicable Diseases Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran., Heydari ST; Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. heydari.st@gmail.com.
Jazyk: angličtina
Zdroj: World journal of cardiology [World J Cardiol] 2022 Dec 26; Vol. 14 (12), pp. 617-625.
DOI: 10.4330/wjc.v14.i12.617
Abstrakt: Background: Cardiac conduction disorders and electrocardiographic (ECG) changes may occur as a manifestation of coronavirus disease 2019 (COVID-19), especially in severe cases.
Aim: To describe conduction system disorders and their association with other electrocardiographic parameters in patients who died of COVID-19.
Methods: In this cross-sectional study, electrocardiographic and clinical data of 432 patients who expired from COVID-19 between August 1 st , 2021, and December 1 st , 2021, in a tertiary hospital were reviewed.
Results: Among 432 patients who died from COVID-19, atrioventricular block (AVB) was found in 40 (9.3%). Among these 40 patients, 28 (6.5%) suffered from 1st degree AVB, and 12 (2.8%) suffered from complete heart block (CHB). Changes in ST-T wave, compatible with myocardial infarction or localized myocarditis, appeared in 189 (59.0%). Findings compatible with myocardial injury, such as fragmented QRS and prolonged QTc, were found in 91 patients (21.1%) and 28 patients (6.5%), respectively. In patients who died of COVID-19, conduction disorder was unrelated to any underlying medical condition. Fragmented QRS, axis deviation, and ST-T changes were significantly related to conduction system disorder in patients who died of COVID-19 ( P value < 0.05).
Conclusion: Conduction system disorders are associated with several other ECG abnormalities, especially those indicative of myocardial ischemia or inflammation. Most patients (73.14%) who died of COVID-19 demonstrated at least one ECG abnormality parameter. Since a COVID-19 patient's ECG gives important information regarding their cardiac health, our findings can help develop a risk stratification method for at-risk COVID-19 patients in future studies.
Competing Interests: Conflict-of-interest statement: The authors declare that they have no competing interests.
(©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze: MEDLINE