Effects of Citric Acid on the Healing Process of Chronic Wound due to Leprosy.

Autor: Passos JRD; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil., Sangaleti CT; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil., Trincaus MR; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil., Prezotto KH; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil., Araújo LO; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil., Techy B; Secretaria Municipal de Saúde de Guarapuava-PR-Brasil, Médico da Estratégia Saúde da Família, Guarapuava, Brasil., Baratieri T; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil., Lentsck MH; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil., Taques GR; Departamento de Medicina, Universidade Estadual de Ponta Grossa, Ponta Grossa, Brasil., Moreira RC; Departamento de Enfermagem, Universidade Estadual do Norte do Paraná, Bandeirantes, Brasil., Silva DCD; Departamento de Enfermagem, 307046Universidade Estadual do Centro-Oeste, Guarapuava, Brasil.
Jazyk: angličtina
Zdroj: The international journal of lower extremity wounds [Int J Low Extrem Wounds] 2023 Jan 05, pp. 15347346221147398. Date of Electronic Publication: 2023 Jan 05.
DOI: 10.1177/15347346221147398
Abstrakt: Objective: The aim was to describe the effects of the use of citric acid in the healing process of chronic leprosy wounds. Approach: This is a case series, carried out with 5 people with chronic leprosy wounds, under continuous care in an outpatient center wound care in the center-south region of Brazil. The intervention protocol consisted of topical application of 3% citric acid (ointment), on the wound bed, in a thin layer of approximately 2 mm, on alternate days, and followed up for a total period of 8 weeks and secondary coverage rayon and gauze. The cases were analyzed regarding wound dimensions, histology and clinical observation. Results: It was observed in all cases better aspect of the wound bed, presence of granulation tissue and decrease of the inflammatory process with predominance of lymphocytes, reduction of bacterial colonies, increase and verticalization of type I collagen fibers, reduction of type III collagen and increased areas of epithelialization. Innovation: There was also a reduction in the level of pain and exudation after the treatment protocol. Conclusions: Therefore, the use of citric acid in leprosy neuropathic wounds is promising and may be a treatment option, considering its cost, clinical management and possible effect on the chronic inflammatory process.
Databáze: MEDLINE