Increasing incidence of Trichophyton tonsurans in Munich-A single-centre observation.

Autor: Pilz JF; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany., Köberle M; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany., Kain A; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany., Seidl P; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany., Zink A; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.; Division of Dermatology and Venereology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Biedermann T; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany., Pilz AC; Department of Dermatology and Venereology, Medical Center, University of Freiburg, Freiburg, Germany.; Center for Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Jazyk: angličtina
Zdroj: Mycoses [Mycoses] 2023 May; Vol. 66 (5), pp. 441-447. Date of Electronic Publication: 2023 Jan 09.
DOI: 10.1111/myc.13563
Abstrakt: Background: Tinea capitis and tinea corporis are highly prevalent fungal skin infections, which globally are mainly caused by Microsporum canis and Trichophyton rubrum, respectively. While in the United States and Great Britain Trichophyton tonsurans is widely prevalent as a causative pathogen, it so far only plays a minor role in Germany.
Objectives: Since the frequency of pathogenic species varies regionally and temporally, this study assesses the proportion of Trichophyton tonsurans infections in the dermatology department of a large university hospital in Germany from 2019 to 2022 and thoroughly characterises the affected patient population.
Patients/methods: This retrospective study at the Technical University of Munich analyses mycological culture results regarding the identified dermatophyte and infection site. Detailed patient and disease-related information on Trichophyton tonsurans positive patients was obtained.
Results: In 2022, 23 patients of 111 dermatophyte culture-positive patients tested positive for Trichophyton tonsurans. This accounted for 20.7% and represented a tenfold increase from 2.1% in 2019. Contact sports were only practiced by 21.7% of patients, and no common hotspot or other linkage could be identified between the cases. Additionally, 47.8% of the patients received a systemic treatment, with 30.4% visiting the clinic more than three times. In 2022, 21.7% were diagnosed with a simultaneous infection of the capillitium and body, whereas this was only observed in 7.1% of cases in 2019 to 2021.
Conclusions: This study suggests an increase of Trichophyton tonsurans infections via several routes of transmission.
(© 2023 The Authors. Mycoses published by Wiley-VCH GmbH.)
Databáze: MEDLINE
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