4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1- c ][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics.

Autor: Drokin RA; Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 ul. Mira, 620002 Yekaterinburg, Russian Federation., Fesenko EA; Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 ul. Mira, 620002 Yekaterinburg, Russian Federation., Mozharovskaia PN; Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 ul. Mira, 620002 Yekaterinburg, Russian Federation., Medvedeva MV; Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 ul. Mira, 620002 Yekaterinburg, Russian Federation., Svalova TS; Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 ul. Mira, 620002 Yekaterinburg, Russian Federation., Kozitsina AN; Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 ul. Mira, 620002 Yekaterinburg, Russian Federation., Esaulkova YL; St. Petersburg Pasteur Institute, 14 ul. Mira, 197101, St. Petersburg, Russian Federation., Volobueva AS; St. Petersburg Pasteur Institute, 14 ul. Mira, 197101, St. Petersburg, Russian Federation., Zarubaev VV; St. Petersburg Pasteur Institute, 14 ul. Mira, 197101, St. Petersburg, Russian Federation., Rusinov VL; Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 ul. Mira, 620002 Yekaterinburg, Russian Federation.; I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, 22/20 ul. S. Kovalevskoi, 620108 Yekaterinburg, Russian Federation.
Jazyk: angličtina
Zdroj: Russian chemical bulletin = Izvestiia Akademii nauk. Seriia khimicheskaia [Russ Chem Bull] 2022; Vol. 71 (11), pp. 2460-2466. Date of Electronic Publication: 2022 Dec 19.
DOI: 10.1007/s11172-022-3674-0
Abstrakt: A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1- c ][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.
(© Springer Science+Business Media LLC 2022.)
Databáze: MEDLINE
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