Risk factors for SARS-CoV-2 transmission in close contacts of adults at high risk of infection due to occupation: results from the contact tracing strategy of the CoVIDA epidemiological surveillance study in Bogotá, Colombia, in 2020-2021.

Autor:	Ramírez Varela A; School of Medicine, Universidad de los Andes, Bogotá, Colombia an-rami2@uniandes.edu.co., Contreras-Arrieta S; School of Medicine, Universidad de los Andes, Bogotá, Colombia., Tamayo-Cabeza G; School of Medicine, Universidad de los Andes, Bogotá, Colombia., Salas Zapata L; Observatorio de Salud, Secretaría Distrital de Salud de Bogotá, Bogotá D.C, Colombia., Caballero-Díaz Y; School of Medicine, Universidad de los Andes, Bogotá, Colombia., Hernández Florez LJ; School of Medicine, Universidad de los Andes, Bogotá, Colombia., Benavidez AP; Epidemiología y Salud Pública, Universidad Nacional de Colombia, Bogotá, Colombia., Laajaj R; Department of Economics, Universidad de los Andes, Bogotá DC, Colombia., De la Hoz F; Departamento de Salud Pública, Universidad Nacional de Colombia, Bogotá DC, Colombia., Buitrago Gutierrez G; Clinical Research Institute, Universidad Nacional de Colombia, Bogotá DC, Colombia., Restrepo S; Department of Food and Chemical Engineering, Universidad de los Andes, Bogotá, Colombia., Behrentz E; Vicerrectoría Administrativa y Financiera, Universidad de los Andes, Bogotá DC, Colombia.
Jazyk:	angličtina
Zdroj:	BMJ open [BMJ Open] 2022 Dec 23; Vol. 12 (12), pp. e062487. Date of Electronic Publication: 2022 Dec 23.
DOI:	10.1136/bmjopen-2022-062487
Abstrakt:	Objectives: To estimate the risk factors for SARS-CoV-2 transmission in close contacts of adults at high risk of infection due to occupation, participants of the CoVIDA study, in Bogotá D.C., Colombia. Setting: The CoVIDA study was the largest COVID-19 intensified sentinel epidemiological surveillance study in Colombia thus far, performing over 60 000 RT-PCR tests for SARS-CoV-2 infection. The study implemented a contact tracing strategy (via telephone call) to support traditional surveillance actions performed by the local health authority. Participants: Close contacts of participants from the CoVIDA study. Primary and Secondary Outcome Measures: SARS-CoV-2 testing results were obtained (RT-PCR with CoVIDA or self-reported results). The secondary attack rate (SAR) was calculated using contacts and primary cases features. Results: The CoVIDA study performed 1257 contact tracing procedures on primary cases. A total of 5551 close contacts were identified and 1050 secondary cases (21.1%) were found. The highest SAR was found in close contacts: (1) who were spouses (SAR=32.7%; 95% CI 29.1% to 36.4%), (2) of informally employed or unemployed primary cases (SAR=29.1%; 95% CI 25.5% to 32.8%), (3) of symptomatic primary cases (SAR of 25.9%; 95% CI 24.0% to 27.9%) and (4) living in households with more than three people (SAR=22.2%; 95% CI 20.7% to 23.8%). The spouses (OR 3.85; 95% CI 2.60 to 5.70), relatives (OR 1.89; 95% CI 1.33 to 2.70) and close contacts of a symptomatic primary case (OR 1.48; 95% CI 1.24 to 1.77) had an increased risk of being secondary cases compared with non-relatives and close contacts of an asymptomatic index case, respectively. Conclusions: Contact tracing strategies must focus on households with socioeconomic vulnerabilities to guarantee isolation and testing to stop the spread of the disease. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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