Spatial Distribution and Physicochemical Properties of Respirable Volcanic Ash From the 16-17 August 2006 Tungurahua Eruption (Ecuador), and Alveolar Epithelium Response In-Vitro.

Autor:	Eychenne J; Université Clermont Auvergne CNRS IRD OPGC Laboratoire Magmas et Volcans Clermont-Ferrand France.; Université Clermont Auvergne CNRS INSERM Institut de Génétique Reproduction et Développement Clermont-Ferrand France., Gurioli L; Université Clermont Auvergne CNRS IRD OPGC Laboratoire Magmas et Volcans Clermont-Ferrand France., Damby D; U.S. Geological Survey California Volcano Observatory Moffett Field CA USA., Belville C; Université Clermont Auvergne CNRS INSERM Institut de Génétique Reproduction et Développement Clermont-Ferrand France., Schiavi F; Université Clermont Auvergne CNRS IRD OPGC Laboratoire Magmas et Volcans Clermont-Ferrand France., Marceau G; Université Clermont Auvergne CNRS INSERM Institut de Génétique Reproduction et Développement Clermont-Ferrand France.; Biochemistry and Molecular Genetic Department University Hospital Clermont-Ferrand France., Szczepaniak C; Université Clermont Auvergne UCA PARTNER Centre Imagerie Cellulaire Santé Clermont-Ferrand France., Blavignac C; Université Clermont Auvergne UCA PARTNER Centre Imagerie Cellulaire Santé Clermont-Ferrand France., Laumonier M; Université Clermont Auvergne CNRS IRD OPGC Laboratoire Magmas et Volcans Clermont-Ferrand France., Gardés E; Université Clermont Auvergne CNRS IRD OPGC Laboratoire Magmas et Volcans Clermont-Ferrand France., Le Pennec JL; Geo-Ocean CNRS Ifremer UMR6538 Plouzané France.; IRD Office for Indonesia & Timor Leste Jalan Kemang Raya Jakarta Indonesia., Nedelec JM; Université Clermont Auvergne Clermont Auvergne INP CNRS ICCF Clermont-Ferrand France., Blanchon L; Université Clermont Auvergne CNRS INSERM Institut de Génétique Reproduction et Développement Clermont-Ferrand France., Sapin V; Université Clermont Auvergne CNRS INSERM Institut de Génétique Reproduction et Développement Clermont-Ferrand France.; Biochemistry and Molecular Genetic Department University Hospital Clermont-Ferrand France.
Jazyk:	angličtina
Zdroj:	GeoHealth [Geohealth] 2022 Dec 01; Vol. 6 (12), pp. e2022GH000680. Date of Electronic Publication: 2022 Dec 01 (Print Publication: 2022).
DOI:	10.1029/2022GH000680
Abstrakt:	Tungurahua volcano (Ecuador) intermittently emitted ash between 1999 and 2016, enduringly affecting the surrounding rural area and its population, but its health impact remains poorly documented. We aim to assess the respiratory health hazard posed by the 16-17 August 2006 most intense eruptive phase of Tungurahua. We mapped the spatial distribution of the health-relevant ash size fractions produced by the eruption in the area impacted by ash fallout. We quantified the mineralogy, composition, surface texture, and morphology of a respirable ash sample isolated by aerodynamic separation. We then assessed the cytotoxicity and pro-inflammatory potential of this respirable ash toward lung tissues in-vitro using A549 alveolar epithelial cells, by electron microscopy and biochemical assays. The eruption produced a high amount of inhalable and respirable ash (12.0-0.04 kg/m 2 of sub-10 μm and 5.3-0.02 kg/m 2 of sub-4 μm ash deposited). Their abundance and proportion vary greatly across the deposit within the first 20 km from the volcano. The respirable ash is characteristic of an andesitic magma and no crystalline silica is detected. Morphological features and surface textures are complex and highly variable, with few fibers observed. In-vitro experiments show that respirable volcanic ash is internalized by A549 cells and processed in the endosomal pathway, causing little cell damage, but resulting in changes in cell morphology and membrane texture. The ash triggers a weak pro-inflammatory response. These data provide the first understanding of the respirable ash hazard near Tungurahua and the extent to which it varies spatially in a fallout deposit. Competing Interests: The authors declare no conflicts of interest relevant to this study. (© 2022 The Authors. GeoHealth published by Wiley Periodicals LLC on behalf of American Geophysical Union.)
Databáze:	MEDLINE
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