| Autor: |
Georgakouli K; Department of Nutrition and Dietetics, University of Thessaly, 42132 Trikala, Greece., Manthou E; Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece., Fatouros IG; Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece., Deli CK; Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece., Koutedakis Y; Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece., Theodorakis Y; Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece., Jamurtas AZ; Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece. |
| Abstrakt: |
Impaired activity of the hypothalamic-pituitary-adrenal axis (HPA-axis) is evident in alcohol use disorder (AUD), and may be implicated in various nutritional and metabolic alterations often seen in individuals with this disorder. The present study examined a possible correlation between HPA-axis activity and nutritional status components in individuals with AUD. Fourteen AUD and fourteen non-AUD males participated; anthropometric and body composition measurements were made, and fasting blood samples were analysed for plasma adrenal corticotropic hormone (ACTH), catecholamines, cortisol and beta-endorphin. Nutrient intake was estimated via a three-day diet record. Waist circumference and waist-to-hip ratio were increased in the AUD group. Thiamine and folic intake were lower in AUD group, although only folic acid intake was insufficient in both AUD and non-AUD groups. Increased epinephrine and norepinephrine were also observed in AUD group compared to non-AUD group. No clear correlation between HPA-axis activity and nutritional status components was found. This study showed that nutrient intake, body composition, and HPA-axis activity were different among AUD and non-AUD individuals. More research on the correlation between nutritional status and HPA-axis activity in AUD individuals should be conducted. |
