Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study.

Autor:	Teixeira LAC; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Dos Santos JM; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Multicenter Program in Physiological Sciences (PPGCF), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., Parentoni AN; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Lima LP; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Multicenter Program in Physiological Sciences (PPGCF), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., Duarte TC; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Brant FP; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., Neves CDC; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Multicenter Program in Physiological Sciences (PPGCF), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., Pereira FSM; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Medicine School, University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., Avelar NCP; Department of Health Sciences, University of Santa Catarina (UFSC), Araranguá 88040-900, Brazil., Danielewicz AL; Department of Health Sciences, University of Santa Catarina (UFSC), Araranguá 88040-900, Brazil., Leopoldino AAO; Postgraduate Program in Health Sciences, Faculty of Medical Science of Minas (FCMMG), Belo Horizonte 30130-110, Brazil., Costa SP; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Arrieiro AN; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., Soares LA; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Prates ACN; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Nobre JNP; Postgraduate Multicenter Program in Physiological Sciences (PPGCF), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., de Carvalho Bastone A; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., de Oliveira VC; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Oliveira MX; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Scheidt Figueiredo PH; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Costa HS; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil., Amaral Mendonça V; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Multicenter Program in Physiological Sciences (PPGCF), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil., Taiar R; MATériaux et Ingénierie Mécanique (MATIM), Université de Reims Champagne-Ardenne, 51100 Reims, France., Rodrigues Lacerda AC; Physiotherapy Department, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Program in Health Sciences (PPGCS), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.; Postgraduate Program in Rehabilitation and Functional Performance (PPGReab), Federal University of Jequitinhonha and Mucuri Valleys, Diamantina 39803-371, Brazil.; Postgraduate Multicenter Program in Physiological Sciences (PPGCF), Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina 39803-371, Brazil.
Jazyk:	angličtina
Zdroj:	Journal of clinical medicine [J Clin Med] 2022 Dec 02; Vol. 11 (23). Date of Electronic Publication: 2022 Dec 02.
DOI:	10.3390/jcm11237175
Abstrakt:	Inflammation is a chronic, sterile, low-grade inflammation that develops with advanced age in the absence of overt infection and may contribute to the pathophysiology of sarcopenia, a progressive and generalized skeletal muscle disorder. Furthermore, a series of biomarkers linked to sarcopenia occurrence have emerged. To aid diagnostic and treatment strategies for low muscle mass in sarcopenia and other related conditions, the objective of this work was to investigate potential biomarkers associated with appendicular lean mass in community-dwelling older women. This is a cross-sectional study with 71 older women (75 ± 7 years). Dual-energy X-ray absorptiometry was used to assess body composition. Plasmatic blood levels of adipokines (i.e., adiponectin, leptin, and resistin), tumor necrosis factor (TNF) and soluble receptors (sTNFr1 and sTNFr2), interferon (INF), brain-derived neurotrophic factor (BDNF), and interleukins (IL-2, IL-4, IL-5, IL-6, IL-8, and IL-10) were determined by enzyme-linked immunosorbent assay. Older women with low muscle mass showed higher plasma levels of adiponectin, sTNFr1, and IL-8 compared to the regular muscle mass group. In addition, higher adiponectin plasma levels explained 14% of the lower appendicular lean mass. High adiponectin plasmatic blood levels can contribute to lower appendicular lean mass in older, community-dwelling women.
Databáze:	MEDLINE
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