DRIFT OF INFLUENA A(H3N2) VIRUS: BIOLOGICAL, ANTIGENIC AND GENETIC PROPERTIES IN EPIDEMIC SEASON 2016-2017 IN RUSSIA AND COUNTRIES OF THE NOTHERN HEMYSPHERE.

Autor: Lvov DK; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Burtseva EI; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Kirillova ES; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Kolobukhina LV; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Mukasheva EA; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Trushakova SV; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Feodoritova EL; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Merkulova LN; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Krasnoslobodtsev KG; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Garina EO; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Fedyakina IT; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Aristova VA; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Vartanyan RV; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Kisteneva LB; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Deryabin PG; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Prilipov AG; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Rosatkevich AG; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Breslav NV; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Kruzhkova IS; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Belyaev AL; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Aksel'Rod EV; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Sadykova GK; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Shlyapnikova OV; D.I. Ivanovsky Institute of Virology FSBI «National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»., Bazarova MV; Clinical Hospital for Infectious Diseases No. 1., Devyatkin AV; Clinical Hospital for Infectious Diseases No. 1.
Jazyk: angličtina
Zdroj: Voprosy virusologii [Vopr Virusol] 2018 Apr 20; Vol. 63 (2), pp. 61-68. Date of Electronic Publication: 2018 Apr 20.
DOI: 10.18821/0507-4088-2018-63-2-61-68
Abstrakt: The article presents the features of the influenza virus circulation for the period from October 2016 to May 2017 in some territories of Russia collaborating with the D.I. Ivanovsky Institute of Virology, Federal State Budgetary Institution "N.F. Gamaleya Federal Research Centre for Epidemiology and Microbiology", Ministry of Health of the Russian Federation. One of the 2016-2017 season's peculiarities in Russia and countries of the Northern hemisphere was the earlier start of an increase in ARD morbidity with peak indexes reached towards the end of December 2016 - January 2017. First, influenza A(H3N2) virus was predominant; then, it was followed by influenza B virus activity observed until the end of the season. The indexes of morbidity were higher than in the previous season, while the rates of hospitalization and mortality were lower, lethal cases being detected in persons 65 years old and older. Epidemic strains of influenza A(H3N2) virus belonged to 3c.2a genetic group, reference strain A/Hong Hong/4408/2014, and its subgroup 3c.2a1, reference A/Bolzano/7/2016, that are antigenically similar. Strains of influenza B virus were antigenically similar to the B/Brisbane/60/2008 vaccine virus. Strains were sensitive to oseltamivir and zanamivir. The share participation of non-influenza ARI viruses was similar to preliminary epidemic seasons. WHO has issued recommendations for influenza virus vaccines composition for 2017-2018 for the Northern hemisphere.
Databáze: MEDLINE