Assessment of the effects of sex, age, and rearing condition on ultrasonic vocalizations elicited by pups during the maternal potentiation paradigm in C57BL/6J mice.

Autor:	Santana-Coelho D; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Womble PD; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Blandin KJ; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Pilcher JB; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., O'Neill GM; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Douglas LA; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Chilukuri SV; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Tran DLK; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Wiley TA; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA., Lugo JN; Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.
Jazyk:	angličtina
Zdroj:	Developmental psychobiology [Dev Psychobiol] 2022 Dec; Vol. 64 (8), pp. e22341.
DOI:	10.1002/dev.22341
Abstrakt:	Isolation-induced ultrasonic vocalizations (USVs) are important to elicit parental retrieval. This behavior is critical for the animal's survival and can be altered in models of developmental disorders. The potentiation of vocalizations in response to reunion with the dam, also called maternal potentiation, has been extensively studied in rats. However, the assessment of this paradigm in mice is scarce. In rats, the potentiation of vocalizations is dependent on rearing conditions. Since mice are the main species used for genetic models of diseases, we aimed to investigate how different factors such as age, sex, and rearing conditions can affect the potentiation of vocalizations in the maternal potentiation paradigm in mice. We carried out experiments using biparental (dam and sire) or uniparental rearing (dam). Pups were tested on postnatal days (PD) 9 or 12. Pups showed increased potentiation in both sexes at PD9 with uniparental rearing. Both rearing conditions and ages changed the repertoire from the first to the second isolation. Spectral parameters were affected by sex, rearing condition and reunion at PD9. At PD12, only duration was altered by reunion. We conclude that the performance of the pups in the maternal potentiation paradigm is dependent on age, sex, and rearing condition. (© 2022 The Authors. Developmental Psychobiology published by Wiley Periodicals LLC.)
Databáze:	MEDLINE
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