Amelanotic Melanoma Treated as Fungal Infection for Years.

Autor: Kuceki G; School of Medicine, University of Utah, Salt Lake, UT, USA., Deacon DC; Department of Dermatology, University of Utah, Salt Lake, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake, UT, USA., Secrest AM; Department of Dermatology, University of Utah, Salt Lake, UT, USA.; Department of Population Health Sciences, University of Utah, Salt Lake, UT, USA.
Jazyk: angličtina
Zdroj: Case reports in dermatological medicine [Case Rep Dermatol Med] 2022 Nov 07; Vol. 2022, pp. 2598965. Date of Electronic Publication: 2022 Nov 07 (Print Publication: 2022).
DOI: 10.1155/2022/2598965
Abstrakt: This study describes a case of amelanotic lentigo maligna melanoma in a 69-year-old female that had been growing for approximately 5 years. The asymptomatic lesion had been previously diagnosed and treated as a fungal skin infection, an inflammatory rash, and an actinic keratosis that did not respond to standard treatments. Biopsy revealed confluent and nested atypical melanocytes at the dermal-epidermal junction, consistent with melanoma in situ. Excisional biopsy revealed invasive lentigo maligna melanoma, Breslow depth 0.3 mm, with positive melanoma in situ at margins. She is now 3 years post-Mohs surgery without recurrence. When working up a patient with a hypopigmented or inflammatory lesion not responding to standard therapies, physicians should always consider biopsy to rule out unusual neoplastic etiologies, such as amelanotic melanomas.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2022 Guilherme Kuceki et al.)
Databáze: MEDLINE
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