The ART of Thromboprophylaxis in the Prevention of Gestational Venous Thromboembolism.

Autor:	Grandone E; Department of Obstetrics and Gynecology, University of Foggia, Foggia, Italy.; Thrombosis and Haemostasis Unit, Fondazione IRCCS 'Casa Sollievo della Sofferenza,' Foggia, Italy.; Department of Obstetrics and Gynecology, The First I.M. Sechenov Moscow State Medical University, Moscow, Russia., Barcellona D; Thrombosis and Haemostasis Unit, Department of Medical Science and Public Health, University of Cagliari, Azienda Ospedaliero-Universitaria di Cagliari, Cagliari, Italy., Intrieri M; Department of Medicine and Health Science 'V. Tiberio,' University of Molise, Campobasso, Italy., Tiscia G; Thrombosis and Haemostasis Unit, Fondazione IRCCS 'Casa Sollievo della Sofferenza,' Foggia, Italy., Nappi L; Department of Obstetrics and Gynecology, University of Foggia, Foggia, Italy., Othman M; Department of Biomedical and Molecular Sciences, School of Medicine, Queen's University, Kingston, Ontario, Canada.; School of Baccalaureate Nursing, St Lawrence College, Kingston, Ontario, Canada.; Department of Clinical Pathology, School of Medicine, Mansoura University, Mansoura, Egypt.
Jazyk:	angličtina
Zdroj:	Seminars in thrombosis and hemostasis [Semin Thromb Hemost] 2023 Jun; Vol. 49 (4), pp. 330-336. Date of Electronic Publication: 2022 Nov 11.
DOI:	10.1055/s-0042-1758062
Abstrakt:	Assisted reproductive techniques (ART) allow infertile couples to conceive. Use of hormones to obtain a controlled ovarian stimulation and an adequate growth of the endometrium preparatory for embryo implantation are not riskless. Among others, thrombotic events can occur during the ovulation induction or pregnancy following ART. As the number of women approaching ART to conceive is steadily increasing, the issue of thrombotic risk in this setting is relevant. Data on the weight of each risk factor and on potential benefit of thromboprophylaxis are largely lacking. In this review, we discuss risk of venous thromboembolism during pregnancy following ART, with a focus on general (i.e.: age, body mass index, thrombophilia, bed rest, transfusions) and ART-specific (i.e., polycystic ovarian syndrome, ovarian hyperstimulation syndrome) risk factors. We also attempt to provide some suggestions to guide clinical practice, based on available data and studies performed outside ART. Competing Interests: None declared. (Thieme. All rights reserved.)
Databáze:	MEDLINE
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