Early post-operative neurodevelopment and visual assessment in neonates with congenital heart disease undergoing cardiac surgery.
Autor: | Cañizo-Vazquez D; BCNatal, Barcelona Center for Maternal Fetal and Neonatal Medicine, Hospital Sant Joan de Déu and Hospital Clinic, University of Barcelona, Barcelona, Spain., Hadley S; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Leonhardt M; BCNatal, Barcelona Center for Maternal Fetal and Neonatal Medicine, Hospital Sant Joan de Déu and Hospital Clinic, University of Barcelona, Barcelona, Spain., Camprubí-Camprubí M; BCNatal, Barcelona Center for Maternal Fetal and Neonatal Medicine, Hospital Sant Joan de Déu and Hospital Clinic, University of Barcelona, Barcelona, Spain. marta.camprubi@sjd.es.; Cardiovascular Research Group, Sant Joan de Déu Research Institute, Barcelona, Spain. marta.camprubi@sjd.es., Sanchez-de-Toledo J; Cardiovascular Research Group, Sant Joan de Déu Research Institute, Barcelona, Spain.; Pediatric Cardiology Department. Sant Joan de Déu Hospital, Barcelona, Spain.; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA. |
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Jazyk: | angličtina |
Zdroj: | Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2023 Jul; Vol. 43 (7), pp. 856-863. Date of Electronic Publication: 2022 Nov 08. |
DOI: | 10.1038/s41372-022-01555-7 |
Abstrakt: | Objective: Assessment of neurobehavior and visual function of newborns with congenital heart disease during the post-operative period to identify infants at risk of neurodevelopmental and visual impairment. Study Design: Prospective study that included 45 newborns who underwent cardiac surgery. Newborn Behavioral Observations test (NBO) and "ML Battery of Optotypes" were used for assessment. Results: The median NBO global score was 2.4 [2.1-2.6]. Total days of oral morphine [p = 0.005] and total days of sedation [p = 0.009] were strongly related to abnormal evaluations. Time of cerebral regional oxygen saturation (CrSO Conclusions: We have demonstrated alterations in attention, autonomic, motor, and oral motor function. Duration of sedative medication, time of CrSO (© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.) |
Databáze: | MEDLINE |
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