When bacteria are phage playgrounds: interactions between viruses, cells, and mobile genetic elements.

Autor: Pfeifer E; Institut Pasteur, Université de Paris Cité, CNRS UMR3525, Microbial Evolutionary Genomics, Paris, France., Sousa JM; Institut Pasteur, Université de Paris Cité, CNRS UMR3525, Microbial Evolutionary Genomics, Paris, France., Touchon M; Institut Pasteur, Université de Paris Cité, CNRS UMR3525, Microbial Evolutionary Genomics, Paris, France., Rocha EP; Institut Pasteur, Université de Paris Cité, CNRS UMR3525, Microbial Evolutionary Genomics, Paris, France. Electronic address: erocha@pasteur.fr.
Jazyk: angličtina
Zdroj: Current opinion in microbiology [Curr Opin Microbiol] 2022 Dec; Vol. 70, pp. 102230. Date of Electronic Publication: 2022 Nov 03.
DOI: 10.1016/j.mib.2022.102230
Abstrakt: Studies of viral adaptation have focused on the selective pressures imposed by hosts. However, there is increasing evidence that interactions between viruses, cells, and other mobile genetic elements are determinant to the success of infections. These interactions are often associated with antagonism and competition, but sometimes involve cooperation or parasitism. We describe two key types of interactions - defense systems and genetic regulation - that allow the partners of the interaction to destroy or control the others. These interactions evolve rapidly by genetic exchanges, including among competing partners. They are sometimes followed by functional diversification. Gene exchanges also facilitate the emergence of cross-talk between elements in the same bacterium. In the end, these processes produce multilayered networks of interactions that shape the outcome of viral infections.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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