| Autor: |
Lai J; Diagnostic Imaging Department, St. Jude Children's Research Hospital, Memphis, Tennessee 38152, USA., Bidelman GM; Department of Speech, Language and Hearing Sciences, Indiana University, Bloomington, Indiana 47408, USA jesyin.v@gmail.com, gbidel@indiana.edu. |
| Jazyk: |
angličtina |
| Zdroj: |
JASA express letters [JASA Express Lett] 2022 Oct; Vol. 2 (10), pp. 102001. |
| DOI: |
10.1121/10.0014815 |
| Abstrakt: |
Objective assays of human cochlear synaptopathy (CS) have been challenging to develop. It is suspected that relative summating potential (SP) changes are different in listeners with CS. In this proof-of-concept study, young, normal-hearing adults were recruited and assigned to a low/high-risk group for having CS based on their extended audiograms (9-16 kHz). SPs to paired-clicks with varying inter-click intervals isolated non-refractory receptor components of cochlear activity. Abrupt increases in SPs to paired- vs single-clicks were observed in high-risk listeners. Critically, exaggerated SPs predicted speech-in-noise and subjective hearing abilities, suggesting relative SP changes to rapid clicks might help identify putative synaptopathic listeners. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
