Analgesia, Sedation, and Anesthesia for Neonates With Cardiac Disease.

Autor:	Smith-Parrish M; Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University School of Medicine, Nashville, Tennessee., Vargas Chaves DP; Columbia Presbyterian Hospital, New York City, New York., Taylor K; Hospital for Sick Children, Toronto, Canada., Achuff BJ; Texas Children's Hospital, Baylor College of Medicine, Houston, Texas., Lasa JJ; Texas Children's Hospital, Baylor College of Medicine, Houston, Texas., Hopper A; Loma Linda University Children's Hospital, Loma Linda, California., Ramamoorthy C; Stanford Children's Hospital, Stanford University, California.
Jazyk:	angličtina
Zdroj:	Pediatrics [Pediatrics] 2022 Nov 01; Vol. 150 (Suppl 2).
DOI:	10.1542/peds.2022-056415K
Abstrakt:	Analgesia, sedation, and anesthesia are a continuum. Diagnostic and/or therapeutic procedures in newborns often require analgesia, sedation, and/or anesthesia. Newborns, in general, and, particularly, those with heart disease, have an increased risk of serious adverse events, including mortality under anesthesia. In this section, we discuss the assessment and management of pain and discomfort during interventions, review the doses and side effects of commonly used medications, and provide recommendations for their use in newborns with heart disease. For procedures requiring deeper levels of sedation and anesthesia, airway and hemodynamic support might be necessary. Although associations of long-term deleterious neurocognitive effects of anesthetic agents have received considerable attention in both scientific and lay press, causality is not established. Nonetheless, an early multimodal, multidisciplinary approach is beneficial for safe management before, during, and after interventional procedures and surgery to avoid problems of tolerance and delirium, which can contribute to long-term cognitive dysfunction. (Copyright © 2022 by the American Academy of Pediatrics.)
Databáze:	MEDLINE
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