[Repeated haploidentical allogeneic hematopoietic stem cell transplantation with TCR αβ/CD19 depletion in patient with primary myelofibrosis. Case report].

Autor:	Kolgaeva EI; National Research Center for Hematology., Vasilyeva VA; National Research Center for Hematology., Kuzmina LA; National Research Center for Hematology., Drokov MY; National Research Center for Hematology., Dovydenko MV; National Research Center for Hematology., Konova ZV; National Research Center for Hematology., Chebotarev DI; National Research Center for Hematology., Kovrigina AM; National Research Center for Hematology., Kamelskih DV; National Research Center for Hematology., Gaponova TV; National Research Center for Hematology., Sokolova MA; National Research Center for Hematology., Subortseva IN; National Research Center for Hematology., Melikyan AL; National Research Center for Hematology., Maschan MA; Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology., Parovichnikova EN; National Research Center for Hematology., Savchenko VG; National Research Center for Hematology.
Jazyk:	ruština
Zdroj:	Terapevticheskii arkhiv [Ter Arkh] 2021 Jul 23; Vol. 93 (7), pp. 805-810. Date of Electronic Publication: 2021 Jul 23.
DOI:	10.26442/00403660.2021.07.200948
Abstrakt:	Indications of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in patients with primary myelofibrosis are intermediate-2 and high-risk group of DIPSS (Dynamic International Prognostic Scoring System), beginning of the disease in childhood. The other adverse factors affect engraftment and survival after allo-HSCT, example partialy matched donor. But the result of allo-HSCT from matched related donors and result of allo-HSCT from haploidentical donors are comparable. The method for haploidentical hematopoietic stem cell transplantation is T-cell-depletion. This is clinical case of T-cell-depleted haploidentical hematopoietic stem cell transplantation in patient with primary myelofibrosis, the diagnosis was established in childhood.
Databáze:	MEDLINE
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