Teenager with acute psychosis due to non-paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis with a successful recovery: A case report.

Autor: Chamlagain R; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Shah S; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Thapa S; Kathmandu University School of Medical Sciences, Dhulikhel, Nepal., Basnet M; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Kandel B; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Paudel BS; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Dhital R; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Pokhrel A; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Khanal P; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal., Paudel S; Institute of Medicine, Tribhuvan University, Maharajgunj, 44600, Nepal.
Jazyk: angličtina
Zdroj: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2022 Sep 28; Vol. 82, pp. 104790. Date of Electronic Publication: 2022 Sep 28 (Print Publication: 2022).
DOI: 10.1016/j.amsu.2022.104790
Abstrakt: Introduction: Anti NMDAR encephalitis is a neuropsychiatric syndromic disease caused by an immunological response. Acute behavioral changes, psychosis, and catatonia are common clinical manifestations, are seizures, amnesia, speech difficulties, dyskinesia, and autonomic dysregulation.
Case Presentation: We discuss the case of a 14-year-old girl who had psychotic symptoms and tested positive for anti-NMDAR antibodies.
Discussion: Patients present with psychiatric symptoms such as delusions, hallucinations, agitation, changes in speech mania, disorganized thinking, catatonia, insomnia, and often seizures. Anti-NMDAR encephalitis should be suspected in teenage patient with acute psychotic symptoms and seizure episodes. A multidisciplinary treatment strategy is required.
Conclusion: The delayed treatment can lead to complications and delayed recovery complicating the disease process so multidisciplinary approach of treatment is necessary.
(© 2022 The Authors.)
Databáze: MEDLINE
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