Effects of Combined Visible and Infrared Light Rhinophototherapy in Patients With Allergic Rhinitis.
| Autor: | Koycu A; Department of Otolaryngology, Head and Neck Surgery, 37505Baskent University, Ankara, Turkey., Bas C; Department of Otolaryngology, Head and Neck Surgery, 37505Baskent University, Ankara, Turkey., Musabak UH; Division of Immunology and Allergic Diseases, 37505Baskent University, Ankara, Turkey., Erbek SS; Department of Otolaryngology, Head and Neck Surgery, 37505Baskent University, Ankara, Turkey., Koca HS; Department of Otolaryngology, Head and Neck Surgery, 255409Yuksek Ihtisas University, Ankara, Turkey., Babakurban ST; Department of Otolaryngology, Head and Neck Surgery, 37505Baskent University, Ankara, Turkey., Bahcecitapar M; Department of Statistics, Faculty of Science, Hacettepe University, Ankara, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | American journal of rhinology & allergy [Am J Rhinol Allergy] 2023 Jan; Vol. 37 (1), pp. 65-73. Date of Electronic Publication: 2022 Oct 20. |
| DOI: | 10.1177/19458924221133898 |
| Abstrakt: | Background: Intranasal phototherapy offers an alternative treatment method for patients with allergic rhinitis who cannot benefit from intranasal corticosteroids and oral antihistamines. Different wavelengths have been tried with promising results. Objective: In this present study, we aimed to investigate the effects of visible light-infrared light phototherapy on clinical improvements together with its cytologic effects in patients with allergic rhinitis. Methods: Patients with confirmed allergic rhinitis were given a 4-week course of intranasal phototherapy treatment. Weekly symptom questionnaires were applied to monitor clinical effects. Nasal lavage specimens were obtained before the start and at the completion of the 4-week therapy. Fluorescence-activated cell sorting analyses of CD16 + , CD24 + , and CD 45 + cells were performed. Statistical analyses are performed of weekly changes in symptoms and cell counts. Results: CD45 + CD16 high CD24 + neutrophil count in nasal lavages decreased significantly whereas CD45 + CD16 dim/- CD24 + eosinophil counts significantly increased and CD45 + granulocyte counts remained unchanged. Symptom scores including nasal itching, nasal discharge, nasal obstruction, sneezing, eye itching, throat itching, and ear itching all statistically decreased compared to baseline at the end of 4 weeks. Conclusion: Four-week course of intranasal phototherapy with visible and infrared light leads to clinical improvement in allergic rhinitis patients. |
| Databáze: | MEDLINE |
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