Racial-ethnic variations in phyllodes tumors among a multicenter United States cohort.

Autor: Nash AL; Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA., Thomas SM; Duke Cancer Institute, Duke University, Durham, North Carolina, USA.; Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA., Nimbkar SN; Brigham & Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Hieken TJ; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA., Ludwig KK; Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA., Jacobs LK; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Miller ME; Department of Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Gallagher KK; Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, USA., Wong J; Department of Surgery, University of California, San Francisco, California, USA., Neuman HB; Department of Surgery, University of Wisconsin, Madison, Wisconsin, USA., Tseng J; Department of Surgery, University of Chicago Medicine, Chicago, Illinois, USA., Hassinger TE; Department of Surgery, University of Virginia Health System, Charlottesville, Virginia, USA., King TA; Brigham & Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Hwang ES; Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.; Duke Cancer Institute, Duke University, Durham, North Carolina, USA., Jakub JW; Department of Surgery, Mayo Clinic, Jacksonville, Florida, USA., Rosenberger LH; Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.; Duke Cancer Institute, Duke University, Durham, North Carolina, USA.
Jazyk: angličtina
Zdroj: Journal of surgical oncology [J Surg Oncol] 2023 Mar; Vol. 127 (3), pp. 369-373. Date of Electronic Publication: 2022 Oct 07.
DOI: 10.1002/jso.27117
Abstrakt: Background and Objectives: Previous studies have identified racial-ethnic differences in the diagnostic patterns and recurrence outcomes of women with phyllodes tumors (PT). However, these studies are generally limited in size and generalizability. We therefore sought to explore racial-ethnic differences in age, tumor size, subtype, and recurrence in a large US cohort of women with PT.
Methods: We performed an 11-institution retrospective review of women with PT from 2007 to 2017. Differences in age at diagnosis, tumor size and subtype, and recurrence-free survival according to race-ethnicity.
Results: Women of non-White race or Hispanic ethnicity were younger at the time of diagnosis with phyllodes tumor. Non-Hispanic Other women had a larger proportion of malignant PT. There were no differences in recurrence-free survival in our cohort.
Conclusions: Differences in age, tumor size, and subtype were small. Therefore, the workup of young women with breast masses and the treatment of women with PT should not differ according to race-ethnicity. These conclusions are supported by our finding that there were no differences in recurrence-free survival.
(© 2022 Wiley Periodicals LLC.)
Databáze: MEDLINE
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