COVID-19 vaccine hesitancy in six geopolitical zones in Nigeria: a cross-sectional survey.

Autor:	Ogunbosi BO; Department of Paediatrics, College of Medicine University of Ibadan and University College Hospital, Ibadan, Oyo State, Nigeria., Alao MA; University College Hospital, Ibadan, Oyo State, Nigeria., Ibrahim OR; Department of Paediatrics, Federal Medical Centre, Kastina, Kastina State, Nigeria., Ayuk AC; Department of Paediatrics, College of Medicine University of Nigeria Enugu Campus, Enugu State, Nigeria., Ibraheem RM; Department of Paediatrics and Child Health, University of Ilorin and University of Ilori, Kwara State, Nigeria., Odimegwu CL; Department of Paediatrics, College of Medicine University of Nigeria Enugu Campus, Enugu State, Nigeria., Ikwuka DC; Department of Human Physiology, College of Health Sciences, Nnamdi Azikiwe University Nnewi Campus, Nnewi, Nigeria., Akintan P; Department of Paediatric, College of Medicine, University of Lagos, Lagos State, Nigeria., Morakinyo O; University College Hospital, Ibadan, Oyo State, Nigeria., Adeyemi AT; University College Hospital, Ibadan, Oyo State, Nigeria., Jega RM; Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospitals Sokoto, Sokoto State, Nigeria., Olowookere TF; Medical Department (Vaccines), GlaxoSmithKline Pharmaceutical Nigeria Ltd, Lagos, Nigeria., Bello OE; University of Medical Sciences Teaching Hospital, Akure, Ondo State, Nigeria., Owolabi BI; Department of Paediatrics, General Hospital, Ilorin, Kwara State, Nigeria., Chukwuyem A; Infection Control and Research Centre, Community Health Department, Federal Medical Centre, Owo, Ondo State, Nigeria., Bukar LM; Department of Paediatrics, University of Maiduguri Teaching Hospital, Maiduguri, Bauchi State, Nigeria., Rasaki A; Department of Paediatrics, Gombe State University and Federal Teaching Hospital Gombe, Gombe State, Nigeria., Issa A; Children Specialist Hospital Ilorin, Kwara State, Nigeria., Ewa AU; Department of Paediatrics, University of Calabar Teaching Hospital, Calabar, Nigeria., Oladokun R; Department of Paediatrics, College of Medicine University of Ibadan and University College Hospital, Ibadan, Oyo State, Nigeria., Akinyinka OO; Department of Paediatrics, College of Medicine University of Ibadan and University College Hospital, Ibadan, Oyo State, Nigeria.
Jazyk:	angličtina
Zdroj:	The Pan African medical journal [Pan Afr Med J] 2022 Jul 06; Vol. 42, pp. 179. Date of Electronic Publication: 2022 Jul 06 (Print Publication: 2022).
DOI:	10.11604/pamj.2022.42.179.34135
Abstrakt:	Introduction: the high expectations that heralded the development of COVID-19 vaccines has been plagued with vaccine hesitancy (VH). The prevalence and associated factors of COVID-19 VH in the six geopolitical zones in Nigeria are explored. Methods: using a cross sectional survey, a pre-tested and validated questionnaire on a "Google form" was distributed via social media platforms and hard copies in the six geopolitical zones of Nigeria. Included, using a chain-reference sampling technique, were healthcare workers (HCW), university students and adults in the general population. Participants who expressed unwillingness to receive COVID-19 vaccine in the event of an available vaccine were considered to have vaccine hesitancy. Frequency and percentage were used to describe categorical variables. Multivariable logistic regression analysis was used to assess for factors associated with VH. Level of significance was set at 5% on two-sided tails test. Results: among 1615 respondents, mean (standard deviation) age was 36.7 (11.3) years, and 847 (52.4%) were males. More than half were healthcare workers (943; 58.4%), 97.4% had at least secondary level of education, and majority 60.5% belonged to the upper social class. The prevalence of VH was 68.5% (1107/1615), and 67.2% preferred foreign manufactured COVID-19 vaccines. On multivariable regression analysis, residence in Northeast (AOR 6.01, 95% CI 2.24, 16.10) and Northwest (AOR 3.33, 95% CI 1, 48, 7.48) geopolitical zones, the Igbo ethnic group (AOR 1.88, 95% 1.10, 3.22), Christians (AOR 1.86, 95% 1.10, 3.14), nurses (AOR 3.50, 95% CI 1.25, 9.80), pharmacist (AOR 5.82, 95% CI 2.12, 16.32) and participants without confidence in foreign vaccines (AOR 4.13, 95% CI 2.99, 5.72) were at higher likelihood of VH. Conclusion: vaccine hesitancy is high among adults in Nigeria, with higher likelihood among the Igbo ethnic group, Christian faith, residence in Northeast and Northwest geopolitical zones and those with an aversion to foreign-made vaccines. Targeted interventions are required for the desired COVID-19 vaccine uptake rate and herd immunity. Competing Interests: The authors declare no competing interests. (Copyright: Babatunde Oluwatosin Ogunbosi et al.)
Databáze:	MEDLINE
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