[Clinical and epidemiological differences and similarities of viral pneumonias in two pandemics].

Autor:	Riquelme O R; Hospital de Puerto Montt, Escuela de Medicina, Universidad San Sebastián, Chile., Rioseco Z ML; Hospital de Puerto Montt, Escuela de Medicina, Universidad San Sebastián, Chile., Riquelme O M; Hospital de Puerto Montt, Escuela de Medicina, Universidad San Sebastián, Chile., Riquelme D J; Hospital de Puerto Montt, Escuela de Medicina, Universidad San Sebastián, Chile., Caro M J, Oyarzún M D; Escuela de Medicina, Hospital de Puerto Montt, Chile., Rincón C M; Escuela de Medicina, Hospital de Puerto Montt, Chile., Bahamonde O C; Escuela de Medicina, Hospital de Puerto Montt, Chile., Gallardo A D; Escuela de Medicina, Hospital de Puerto Montt, Chile., Bedoya J J; Escuela de Medicina, Hospital de Puerto Montt, Chile., Medina A C; Hospital de Puerto Montt, Escuela de Medicina, Universidad San Sebastián, Chile., Inzunza P C; Hospital de Puerto Montt, Escuela de Medicina, Universidad San Sebastián, Chile.
Jazyk:	Spanish; Castilian
Zdroj:	Revista medica de Chile [Rev Med Chil] 2022 Mar; Vol. 150 (3), pp. 316-323.
DOI:	10.4067/S0034-98872022000300316
Abstrakt:	Background: In a decade, we faced two pandemic viruses, influenza A H1N1pdm09 and SARS CoV-2, whose most serious manifestation is pneumonia. Aim: To compare the clinical, epidemiological and management aspects of pneumonias caused by each pandemic virus in adults requiring hospitalization. Material and Methods: Comparative, observational study carried out at a regional Chilean hospital, including 75 patients with influenza A H1N1pdm09 prospectively studied in 2009 and 142 patients with SARS-CoV-2 studied in 2020. Results: Patients with SARS-CoV-2 pneumonia were older (56 and 39.7 years respectively, p < 0.01) and had significantly more comorbidities. Cough, fever and myalgias were more frequent in influenza. Dyspnea was more frequent in COVID-19. Patients with COVID-19 had more extensive lung involvement and a longer hospitalization (13.6 and 8.6 days respectively, p = 0.01). There was no difference on ICU admission requirements and mortality attributable to pneumonia. Patients with influenza had greater APACHE scores and a higher frequency of a PaO2/FiO2 ratio ≤ 200. During COVID-19pandemic chest sean replaced x-ray examination. Also high-flow nasal cannulas and awake prone position ventilation were added as treatments. Conclusions: COVID-19 patients were older, had fewer classic flu symptoms but more dyspnea and longer hospitalization periods than patients with influenza.
Databáze:	MEDLINE
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