Potential origins of fish toti-like viruses in invertebrates.

Autor: Tighe AJ; Marine Institute, Oranmore, Co. Galway H91 R673, Ireland.; Area 52 Research Group, School of Biology and Environmental Science/Earth Institute, University College Dublin, Dublin 4, Ireland., Ruane NM; Marine Institute, Oranmore, Co. Galway H91 R673, Ireland., Carlsson J; Area 52 Research Group, School of Biology and Environmental Science/Earth Institute, University College Dublin, Dublin 4, Ireland.
Jazyk: angličtina
Zdroj: The Journal of general virology [J Gen Virol] 2022 Sep; Vol. 103 (9).
DOI: 10.1099/jgv.0.001775
Abstrakt: The virus family Totiviridae had originally been considered to include only viruses which infected fungal and protist hosts, but since 2006 a growing number of viruses found in invertebrates and fish have been shown to cluster phylogenetically within this family. These Totiviridae- like, or toti-like, viruses do not appear to belong within any existing genera of Totiviridae , and whilst a number of new genus names have been suggested, none has yet been universally accepted. Within this growing number of toti-like viruses from animal hosts, there exists emerging viral threats particularly to aquaculture, namely Infectious myonecrosis virus in whiteleg shrimp and Piscine myocarditis virus (PMCV) in Atlantic salmon ( Salmo salar ). PMCV in particular continues to be an issue in salmon aquaculture as a number of questions remain unanswered about how the virus is transmitted and the route of entry into host fish. Using a phylogenetic approach, this study shows how PMCV and the other fish toti-like viruses probably have deeper origins in an arthropod host. Based on this, it is hypothesized that sea lice could be acting as a vector for PMCV, as seen with other RNA viruses in Atlantic salmon aquaculture and in the toti-like Cucurbit yellows-associated virus which is spread by the greenhouse whitefly Trialeurodes vaporariorum .
Databáze: MEDLINE