Hemorrhagic Disease of the Newborn: A Case Series Illustrating Preventable Harm.

Autor: Sellers A; Austin Sellers, MS, Institue of Clinical and Translational Research, Johns Hopkins All Children's Hospital, St. Petersburg, FL., Lew A; Alicia Lew, MD, Department of Pediatrics, University of South Florida College of Medicine, Tampa, FL., Tudyk M; Miriam Tudyk, MD, Department of Pediatrics, Johns Hopkins All Children's Hospital, St. Petersburg, FL., Nakagawa TA; Thomas A. Nakagawa, MD, Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Florida College of Medicine, Jacksonville, FL., Sochet AA; Anthony A. Sochet, MD, MSc, Division of Pediatric Critical Care Medicine, Johns Hopkins All Children's Hospital, St. Petersburg, FL; Anthony A. Sochet, MD, MSc, Department of Anesthesia and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: Anthony.Sochet@jhmi.edu.
Jazyk: angličtina
Zdroj: Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners [J Pediatr Health Care] 2023 Jan-Feb; Vol. 37 (1), pp. 67-73. Date of Electronic Publication: 2022 Sep 16.
DOI: 10.1016/j.pedhc.2022.08.004
Abstrakt: Newborns are susceptible to postnatal Vitamin K deficiencies from limited placental transfer, gastrointestinal absorption, and bioavailability in breast milk and formula preparations. For over 50 years, the American Academy of Pediatrics has recommended prophylactic vitamin K to prevent hemorrhagic disease in newborns. Yet, public skepticism contributes to increasing refusal rates. We present three cases of vitamin K-dependent bleeding following parental refusal of postnatal prophylaxis. Two patients experienced intracranial hemorrhage with resultant neurological devastation and mortality, respectively. The third child presented with symptomatic hematuria. Perinatal providers must partner with families and advocate vitamin K prophylaxis to limit unnecessary morbidity and mortality.
Competing Interests: Declaration of Competing Interest Thomas A. Nakagawa received author royalties from Wolters Kluwer, UpToDate. The remaining authors have no conflicts of interest to disclose.
(Copyright © 2022 National Association of Pediatric Nurse Practitioners. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: