RISK OF PRENEOPLASTIC LESIONS IN MUCOSAL PROJECTIONS OF DIFFERENT SIZES OF THE COLUMNAR EPITHELIUM IN THE LOWER ESOPHAGUS.

Autor:	Copetti H; Universidade Federal de Santa Maria - Santa Maria (RS), Brazil., Copetti L; Universidade Federal de Santa Maria - Santa Maria (RS), Brazil., Copetti L; Universidade Federal de Santa Maria - Santa Maria (RS), Brazil., Felin GD; Universidade Franciscana - Santa Maria (RS), Brazil., Felin GD; Universidade Franciscana - Santa Maria (RS), Brazil., Felin CD; Pontifícia Universidade Católica do Rio Grande do Sul - Porto Alegre (RS), Brazil., Felin FD; Hospital Ernesto Dornelles - Porto Alegre (RS), Brazil., Chiesa V; Universidade Federal de Ciências da Saúde de Porto Alegre - Porto Alegre (RS), Brazil.
Jazyk:	angličtina
Zdroj:	Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery [Arq Bras Cir Dig] 2022 Sep 09; Vol. 35, pp. e1674. Date of Electronic Publication: 2022 Sep 09 (Print Publication: 2022).
DOI:	10.1590/0102-672020220002e1674
Abstrakt:	Background: Barrett's esophagus is an acquired condition that predisposes to the development of esophageal adenocarcinoma. Aims: The aim of this study was to establish an association between the endoscopic and the histopathological findings regarding differently sized endoscopic columnar epithelial mucosa projections in the low esophagus, under 3.0 cm in the longitudinal extent. Methods: This is a prospective study, including 1262 patients who were submitted to upper gastrointestinal endoscopy in the period from July 2015 to June 2017. The suspicious projections were measured and subdivided into three groups according to the sizes encountered (Group I: <0.99 cm; Group II: 1.0-1.99 cm; and Group III: 2.0-2.99 cm), and biopsies were then performed. Results: There was a general prevalence of suspicious lesions of 6.42% and of confirmed Barrett's lesions of 1.17%, without a general significant statistical difference among groups. However, from Groups I and II to Group III, the differences were significant, showing that the greater the lesion, the higher the probability of Barrett's esophagus diagnosis. The absolute number of Barrett's lesions was 7, 9, and 6 for Groups I, II, and III, respectively. Conclusions: The findings led to the conclusion that even projections under 3.0 cm present a similar possibility of evolution to Barrett's esophagus. If, on the one hand, short segments are more prevalent, on the other hand, the long segments have the higher probability of Barrett's esophagus diagnosis, which is why biopsies are required in all suspicious segments.
Databáze:	MEDLINE
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