Local recurrence risk in head and neck basal cell carcinoma.

Autor:	Szewczyk M; Department of Head and Neck Surgery, Poznan University of Medical Sciences, The Greater Poland Cancer Center, Poznan, Poland., Pazdrowski J; Department of Head and Neck Surgery, Poznan University of Medical Sciences, The Greater Poland Cancer Center, Poznan, Poland., Pabiszczak M; Katedra i Klinika Chirurgii Głowy, Szyi i Onkologii Laryngologicznej. Uniwersytet Medyczny w Poznaniu. Wielkopolskie Centrum Onkologii., Więckowska B; Katedra i Zakład Informatyki i Statystyki., Dańczak-Pazdrowska A; Klinika Dermatologii. Uniwersytet Medyczny w Poznaniu., Golusiński W; Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu Wydział Lekarski II Katedra i Klinika Chirurgii Głowy, Szyi i Onkologii Laryngologicznej.
Jazyk:	angličtina
Zdroj:	Otolaryngologia polska = The Polish otolaryngology [Otolaryngol Pol] 2022 Jun 01; Vol. 76 (4), pp. 1-5.
DOI:	10.5604/01.3001.0015.8568
Abstrakt:	Purpose: The aim of the study was to ascertain the risk factors of local recurrence in primary basal cell carcinoma of the head and neck Material and methods: A retrospective analysis of 545 patients with head and neck primary basal cell carcinoma treated in years 2008 - 2018 was done. The following data was recorded: age, sex, tumor site, histological subtype, greatest dimension, margin status, experience of operating surgeon and local recurrence Results: Most of the tumors were located nose (165; 30,2%) and auricle (119; 21,8%). The most common pathological subtype was nodular (119; 21,8%). Three hundred and ninety-four tumors (72,2%) were under 20mm in diameter. Positive surgical margins were noted in 107 (19,6%) cases. Local recurrence was observed in 52 (9,5%) cases, of which 29 (29/107; 27%) had positive surgical margins, in 23 (23/438; 5,2%) cases margins were free, which was the only statistically significant factor (p<0,001; OR 6,71; CI 3,69 - 12,2). Conclusions: The results of our study have shown that positive surgical margin remains the strongest risk factor for local recurrence. With surgical excision being the gold standard of treatment the greatest emphasis should be placed on avoiding such scenario in high risk patients.
Databáze:	MEDLINE
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